Olfactory dysfunction at six months after coronavirus disease 2019 infection

被引:12
作者
Leedman, S. R. [1 ]
Sheeraz, M. [2 ]
Sanfilippo, P. G. [3 ]
Edgar, D. W. [4 ,5 ,6 ]
D'Aulerio, G., V [5 ]
Robb, D. M. [5 ]
Richards, T. [5 ]
Blyth, C. C. [5 ]
Mackey, D. A. [5 ,7 ]
机构
[1] Sir Charles Gairdner Hosp, Dept Otolaryngol Head & Neck Surg, Hosp Ave, Nedlands, WA 6009, Australia
[2] Fiona Stanley Hosp, COVID 19 Res Response, Murdoch, WA, Australia
[3] Univ Melbourne, Royal Victorian Eye & Ear Hosp, Ctr Eye Res Australia, East Melbourne, Australia
[4] Univ Notre Dame Australia, Inst Hlth Res, Fremantle, WA, Australia
[5] Univ Western Australia, Fac Hlth & Med Sci, Perth, WA, Australia
[6] Fiona Stanley Hosp, Physiotherapy Dept, Murdoch, WA, Australia
[7] Univ Western Australia, Lions Eye Inst, Ctr Ophthalmol & Visual Sci, Perth, WA, Australia
关键词
Coronavirus; COVID-19; Anosmia; Hyposmia; Olfactory Impairment; POPULATION; SMELL;
D O I
10.1017/S0022215121002085
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective This study aimed to assess olfactory dysfunction in patients at six months after confirmed coronavirus disease 2019 infection. Methods Coronavirus disease 2019 positive patients were assessed six months following diagnosis. Patient data were recoded as part of the adapted International Severe Acute Respiratory and Emerging Infection Consortium Protocol. Olfactory dysfunction was assessed using the University of Pennsylvania Smell Identification Test. Results Fifty-six patients were included. At six months after coronavirus disease 2019 diagnosis, 64.3 per cent of patients (n = 36) were normosmic, 28.6 per cent (n = 16) had mild to moderate microsmia and 7 per cent (n = 4) had severe microsmia or anosmia. There was a statistically significant association between older age and olfactory dysfunction. Hospital or intensive care unit admission did not lead to worse olfactory outcomes compared to those managed in the out-patient setting. Conclusion At six months after coronavirus disease 2019 diagnosis, approximately two-thirds of patients will be normosmic. This study is the first to describe six-month outcomes for post-coronavirus disease 2019 patients in terms of olfactory dysfunction.
引用
收藏
页码:839 / 843
页数:5
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