Malaria - an overview

被引：186

作者：

Tuteja, Renu ^{[1
]}

机构：

[1] Int Ctr Genet Engn & Biotechnol, Malaria Grp, New Delhi 110067, India

来源：

FEBS JOURNAL | 2007年 / 274卷 / 18期

关键词：

cerebral malaria; erythrocytes; malaria life cycle; malaria parasite; mosquito; parasite genome; parasite transcriptome; pathogenesis; Plasmodium falciparum; red blood cells;

D O I：

10.1111/j.1742-4658.2007.05997.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Malaria is caused by protozoan parasites of the genus Plasmodium and is a major cause of mortality and morbidity worldwide. These parasites have a complex life cycle in their mosquito vector and vertebrate hosts. The primary factors contributing to the resurgence of malaria are the appearance of drug-resistant strains of the parasite, the spread of insecticide-resistant strains of the mosquito and the lack of licensed malaria vaccines of proven efficacy. This minireview includes a summary of the disease, the life cycle of the parasite, information relating to the genome and proteome of the species lethal to humans, Plasmodium falciparum, together with other recent developments in the field.

引用

页码：4670 / 4679

页数：10

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