Purpose of Review The goal of this review is to discuss the data on natural alternative sweeteners and their effects on glucose homeostasis and other metabolic parameters within the past five years. We sought to answer whether common natural alternative sweeteners have a positive or negative effect on glucose control in both human and animalmodels, and whether the data supports their widespread use as a tool to help reduce the prevalence of diabetes and associated comorbid conditions. Recent Findings Recent studies suggest that natural alternative sweeteners may reduce hyperglycemia, improve lipid metabolism, and have antioxidant effects particularly in those that have baseline diabetes. Summary Diabetes and metabolic syndrome have become a global healthcare crisis and the sugar overconsumption plays a major role. The use of artificial sweeteners has become more prevalent to improve insulin resistance in those with diabetes, obesity, and metabolic syndrome, although the evidence does not support this result. There are however some promising data to suggest that natural alternative sweeteners may be a better alternative to sugar and artificial sweeteners.
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St Clara Hosp, St Clara Res Ltd, Basel, Switzerland
Univ Hosp Basel, Dept Biomed, Basel, SwitzerlandSt Clara Hosp, St Clara Res Ltd, Basel, Switzerland
Woelnerhanssen, Bettina K.
Meyer-Gerspach, Anne Christin
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St Clara Hosp, St Clara Res Ltd, Basel, SwitzerlandSt Clara Hosp, St Clara Res Ltd, Basel, Switzerland
Meyer-Gerspach, Anne Christin
Beglinger, Christoph
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St Clara Hosp, St Clara Res Ltd, Basel, SwitzerlandSt Clara Hosp, St Clara Res Ltd, Basel, Switzerland
Beglinger, Christoph
Islam, Md Shahidul
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St Clara Hosp, St Clara Res Ltd, Basel, Switzerland
Univ KwaZulu Natal, Sch Life Sci, Dept Biochem, Westville Campus, ZA-4000 Durban, South AfricaSt Clara Hosp, St Clara Res Ltd, Basel, Switzerland
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St Clara Res Ltd, St Claraspital, CH-4002 Basel, Switzerland
Univ Basel, Fac Med, CH-4001 Basel, SwitzerlandSt Clara Res Ltd, St Claraspital, CH-4002 Basel, Switzerland
Teysseire, Fabienne
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Bordier, Valentine
Beglinger, Christoph
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Univ Basel, Fac Med, CH-4001 Basel, SwitzerlandSt Clara Res Ltd, St Claraspital, CH-4002 Basel, Switzerland
Beglinger, Christoph
Woelnerhanssen, Bettina K.
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St Clara Res Ltd, St Claraspital, CH-4002 Basel, Switzerland
Univ Basel, Fac Med, CH-4001 Basel, SwitzerlandSt Clara Res Ltd, St Claraspital, CH-4002 Basel, Switzerland
机构:
Univ Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, Malaysia
Razak, Fathilah Abdul
Baharuddin, Baizatul Amirah
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Univ Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, Malaysia
Baharuddin, Baizatul Amirah
Akbar, Elisya Farha Mohd.
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Univ Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, Malaysia
Akbar, Elisya Farha Mohd.
Norizan, Amira Hanim
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Univ Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, Malaysia
Norizan, Amira Hanim
Ibrahim, Nur Fazilah
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Univ Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, MalaysiaUniv Malaya, Fac Dent, Dept Oral & Craniofacial Sci, Kuala Lumpur 50603, Malaysia