Chemoradiation therapy for squamous cell carcinoma of the external auditory canal: A meta-analysis

被引：67
作者：
Takenaka, Yukinori [1 ]
Cho, Hironori [1 ]
Nakahara, Susumu [1 ]
Yamamoto, Yoshifumi [1 ]
Yasui, Toshimichi [1 ]
Inohara, Hidenori [1 ]
机构：
[1] Osaka Univ, Grad Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Suita, Osaka, Japan
来源：
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2015年 / 37卷 / 07期
关键词：
external auditory canal; squamous cell carcinoma; chemoradiation therapy; surgery; complication; TEMPORAL BONE RESECTION; MIDDLE-EAR; INTRAARTERIAL CHEMOTHERAPY; MALIGNANT-TUMORS; ADVANCED HEAD; NECK-CANCER; RADIOTHERAPY; MANAGEMENT; OUTCOMES; CHEMORADIOTHERAPY;
D O I：
10.1002/hed.23698
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
BackgroundThe standard treatment for advanced external auditory canal squamous cell carcinoma (SCC) is subtotal temporal bone resection and postoperative radiation therapy (RT), whereas chemoradiation therapy (CRT) is used in some institutions to improve patient prognosis. The purpose of this study was to evaluate the efficacy of CRT in external auditory canal SCC treatment. MethodsMeta-analyses of external auditory canal SCC studies were performed. We extracted 5-year overall survival rates and number of patients for aggregate patient data, and types of treatment and outcomes for individual patient data. ResultsThe 5-year overall survival rate of 752 patients was 57%. In the individual patient data meta-analysis, the 5-year overall survival rates of patients who received surgery RT, preoperative CRT, definitive CRT, and postoperative CRT were 53.5%, 85.7%, 43.6%, and 0%, respectively. ConclusionOur data suggest that preoperative CRT may improve the survival of surgically treated patients with external auditory canal SCC and that definitive CRT may be equivalent to surgical resection. (c) 2014 Wiley Periodicals, Inc. Head Neck 37: 1073-1080, 2015
引用
收藏
页码：1073 / 1080
页数：8
相关论文
共 42 条
[31]   EFFICACY OF SURGICAL TREATMENTS FOR SQUAMOUS-CELL CARCINOMA OF THE TEMPORAL BONE - A LITERATURE-REVIEW [J].
PRASAD, S ;
JANECKA, IP .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1994, 110 (03) :270-280
[32]  
Rasch CRN, 2011, CANCER-AM CANCER SOC, V117, P874, DOI 10.1002/cncr.25577
[33]   Intra-arterial Versus Intravenous Chemoradiation for Advanced Head and Neck Cancer: Results of a Randomized Phase 3 Trial [J].
Rasch, Coen R. N. ;
Hauptmann, Michael ;
Schornagel, Jan ;
Wijers, Oda ;
Buter, Jan ;
Gregor, Theo ;
Wiggenraad, Ruud ;
de Boer, Jan Paul ;
Ackerstaff, Annemiek H. ;
Kroger, Robert ;
Hoebers, Frank J. P. ;
Balm, Alfons J. M. .
CANCER, 2010, 116 (09) :2159-2165
[34]   Targeted infusions of supradose cisplatin with systemic neutralization for carcinomas invading the temporal bone [J].
Robbins, KT ;
Pelliteri, PK ;
Vicario, D ;
Kerber, CW ;
Robertson, JH ;
Hanchett, C ;
Howell, SB .
SKULL BASE SURGERY, 1996, 6 (02) :69-76
[35]  
Sato K, 2008, JPN J HEAD NECK CANC, V34, P582
[36]   Concomitant Chemoradiotherapy as a Standard Treatment for Squamous Cell Carcinoma of the Temporal Bone [J].
Shiga, Kiyoto ;
Ogawa, Takenori ;
Maki, Atsuko ;
Amano, Masanori ;
Kobayashi, Toshimitsu .
SKULL BASE-AN INTERDISCIPLINARY APPROACH, 2011, 21 (03) :153-158
[37]   Current trends in initial management of laryngeal cancer: the declining use of open surgery [J].
Silver, Carl E. ;
Beitler, Jonathan J. ;
Shaha, Ashok R. ;
Rinaldo, Alessandra ;
Ferlito, Alfio .
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2009, 266 (09) :1333-1352
[38]  
Sterne JAC, 2001, COCHRANE HDB SYSTEMA
[39]   Concurrent Superselective Intra-arterial Chemotherapy and Radiotherapy for Late-Stage Squamous Cell Carcinoma of the Temporal Bone [J].
Sugimoto, Hisashi ;
Ito, Makoto ;
Yoshida, Shinya ;
Hatano, Miyako ;
Yoshizaki, Tomokazu .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2011, 120 (06) :372-376
[40]  
Uchida M, 2012, J JPN SOC HEAD NECK, V22, P41
12345