Boosting Recovery During Sleep by Means of Auditory Stimulation

被引：15

作者：

Krugliakova, Elena ^{[1
,2
]}

Skorucak, Jelena ^{[1
,2
]}

Sousouri, Georgia ^{[1
,2
,3
]}

Leach, Sven ^{[1
,2
]}

Snipes, Sophia ^{[1
,2
,4
]}

Ferster, Maria Laura ^{[3
]}

Da Poian, Giulia ^{[3
]}

Karlen, Walter ^{[3
]}

Huber, Reto ^{[1
,2
,5
]}

机构：

[1] Univ Zurich, Univ Childrens Hosp Zurich, Child Dev Ctr, Zurich, Switzerland

[2] Univ Zurich, Univ Childrens Hosp Zurich, Childrens Res Ctr, Zurich, Switzerland

[3] Swiss Fed Inst Technol, Dept Hlth Sci & Technol, Mobile Hlth Syst Lab, Zurich, Switzerland

[4] Swiss Fed Inst Technol, Dept Hlth Sci & Technol, Neural Control Movement Lab, Zurich, Switzerland

[5] Univ Zurich, Psychiat Hosp, Dept Child & Adolescent Psychiat & Psychotherapy, Zurich, Switzerland

来源：

FRONTIERS IN NEUROSCIENCE | 2022年 / 16卷

关键词：

auditory stimulation; non-rapid eye movement sleep (NREM); sleep homeostasis; recovery; slow waves; EEG POWER-DENSITY; MEMORY CONSOLIDATION; SLOW OSCILLATIONS; K-COMPLEX; DEPRIVATION; WAVES; SYNCHRONIZATION; HOMEOSTASIS; PLASTICITY; FREQUENCY;

D O I：

10.3389/fnins.2022.755958

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Sufficient recovery during sleep is the basis of physical and psychological well-being. Understanding the physiological mechanisms underlying this restorative function is essential for developing novel approaches to promote recovery during sleep. Phase-targeted auditory stimulation (PTAS) is an increasingly popular technique for boosting the key electrophysiological marker of recovery during sleep, slow-wave activity (SWA, 1-4 Hz EEG power). However, it is unknown whether PTAS induces physiological sleep. In this study, we demonstrate that, when applied during deep sleep, PTAS accelerates SWA decline across the night which is associated with an overnight improvement in attentional performance. Thus, we provide evidence that PTAS enhances physiological sleep and demonstrate under which conditions this occurs most efficiently. These findings will be important for future translation into clinical populations suffering from insufficient recovery during sleep.

引用

页数：13

共 55 条

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