Nickel/Zinc Iodide Co-catalytic Asymmetric [2+2] Cycloaddition Reactions of Azabenzonorbornadienes with Terminal Alkynes

被引：24

作者：

Chen, Jingchao ^{[1
]}

Xu, Xin ^{[1
]}

He, Zhenxiu ^{[1
]}

Qin, Hongyu ^{[1
]}

Sun, Weiqing ^{[1
]}

Fan, Baomin ^{[1
,2
]}

机构：

[1] Yunnan Minzu Univ, YMU HKBU Joint Lab Tradit Nat Med, Yuehua St, Kunming 650500, Yunnan, Peoples R China

[2] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Yuehua St, Kunming 650500, Yunnan, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 03期

基金：

中国国家自然科学基金;

关键词：

nickel; zinc; cycloaddition; alkyne; azabenzonorbornadiene; RING-OPENING REACTIONS; BICYCLIC ALKENES; NORBORNADIENE DERIVATIVES; OXABICYCLIC ALKENES; OXABENZONORBORNADIENES; CYCLOPROPANATION; CYCLIZATION; COMPLEXES; ALCOHOLS; AMINES;

D O I：

10.1002/adsc.201701133

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The asymmetric [2+2] cycloaddition reactions of alkenes with alkynes are interesting as it has provided a powerful method for the construction of fused and strained cyclobutenes with multiple chiral centers. In this paper, we report the establishment of a dual catalysts system comprising nickel and zinc, which allowed the asymmetric [2+ 2] cycloaddition reactions of azabenzonorbornadienes with terminal alkynes in good yields and excellent enantioselectivities.

引用

页码：427 / 431

页数：5

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