Nickel/Zinc Iodide Co-catalytic Asymmetric [2+2] Cycloaddition Reactions of Azabenzonorbornadienes with Terminal Alkynes

被引：23
作者：
Chen, Jingchao [1 ]
Xu, Xin [1 ]
He, Zhenxiu [1 ]
Qin, Hongyu [1 ]
Sun, Weiqing [1 ]
Fan, Baomin [1 ,2 ]
机构：
[1] Yunnan Minzu Univ, YMU HKBU Joint Lab Tradit Nat Med, Yuehua St, Kunming 650500, Yunnan, Peoples R China
[2] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Yuehua St, Kunming 650500, Yunnan, Peoples R China
来源：
ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 03期
基金：
中国国家自然科学基金;
关键词：
nickel; zinc; cycloaddition; alkyne; azabenzonorbornadiene; RING-OPENING REACTIONS; BICYCLIC ALKENES; NORBORNADIENE DERIVATIVES; OXABICYCLIC ALKENES; OXABENZONORBORNADIENES; CYCLOPROPANATION; CYCLIZATION; COMPLEXES; ALCOHOLS; AMINES;
D O I：
10.1002/adsc.201701133
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The asymmetric [2+2] cycloaddition reactions of alkenes with alkynes are interesting as it has provided a powerful method for the construction of fused and strained cyclobutenes with multiple chiral centers. In this paper, we report the establishment of a dual catalysts system comprising nickel and zinc, which allowed the asymmetric [2+ 2] cycloaddition reactions of azabenzonorbornadienes with terminal alkynes in good yields and excellent enantioselectivities.
引用
收藏
页码：427 / 431
页数：5
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