Integrated management of soil organic matter and nutritional status of crop plants is essential to sustain the production of organic farming systems. Thus, a 2-year field experiment was conducted to examine the effects of soil additions (192 kg N ha(-1), humic+192 kg N ha(-1), humic+144 kg N ha(-1) and humic+96 kg N ha(-1)) and foliar applications (amino acids, Azotobacter+yeast, and amino acids plus Azotobacter+yeast) as various fertilizer resources on growth and yield of wheat. Results showed that humic+192 kg N ha(-1) x amino acids plus Azotobacter+yeast were the effective combination for producing the highest values of flag leaf area, total dry weight, tiller number m(-2), spike weight m(-2), and grain yield ha(-1). Under foliar application of amino acids plus Azotobacter+yeast, reducing N supply from recommended rate (192 kg N ha(-1)) to 144 kg N ha(-1)+ humic achieved higher values of all yield traits, with a saving of 25% of applied mineral nitrogen as well as enhancing nitrogen use efficiency.