Synthesis of 2-Oxopyridine-Fused 1,3-Diazaheterocyclic Compounds via a Three-Component Reaction

被引：5

作者：

Alizadeh, Abdolali ^{[1
]}

Mikaeili, Azadeh ^{[1
]}

Firuzyar, Tahereh ^{[1
]}

Ahmadi, Mahdi ^{[1
]}

机构：

[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran

来源：

HELVETICA CHIMICA ACTA | 2011年 / 94卷 / 07期

关键词：

HETEROCYCLIC KETENE AMINALS; AZA-ENE REACTION; EFFICIENT SYNTHESIS; ROUTE;

D O I：

10.1002/hlca.201000453

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and simple route for the preparation of 2-oxopyridine-fused 1,3-diazaheterocyclic compounds via a three component reaction is described. It involves the reaction between alkylenediamines 1, 1,1-bis(methylsulfanyl)-2-nitroethene, and alkyl prop-2-ynoates 2 in refluxing THF (Table). The structures were corroborated by spectroscopic (IR, (1)H- and (13)C-NMR, and EI-MS) and elemental analyses. A plausible mechanism for this type of cyclization is proposed (Scheme).

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页码：1343 / 1346

页数：4

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