First Human Case of Fatal Halicephalobus gingivalis Meningoencephalitis in Australia

被引：17

作者：

Lim, Chuan Kok ^{[1
,2
]}

Crawford, April ^{[3
]}

Moore, Casey V. ^{[1
]}

Gasser, Robin B. ^{[4
]}

Nelson, Renjy ^{[5
]}

Koehler, Anson V. ^{[4
]}

Bradbury, Richard S. ^{[6
]}

Speare, Rick ^{[7
,8
]}

Dhatrak, Deepak ^{[3
]}

Weldhagen, Gerhard F. ^{[1
]}

机构：

[1] SA Pathol, Dept Microbiol, Adelaide, SA, Australia

[2] Univ Adelaide, Adelaide, SA, Australia

[3] SA Pathol, Dept Histopathol, Adelaide, SA, Australia

[4] Univ Melbourne, Fac Vet Sci, Melbourne, Vic 3010, Australia

[5] Royal Adelaide Hosp, Adelaide, SA 5000, Australia

[6] Cent Queensland Univ, Sch Med & Appl Sci, Rockhampton, Qld 4702, Australia

[7] James Cook Univ, Coll Publ Hlth Med & Vet Sci, Townsville, Qld 4811, Australia

[8] Trop Hlth Solut, Townsville, Qld, Australia

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2015年 / 53卷 / 05期

关键词：

DELETRIX INFECTION; MICRONEMA-DELETRIX; ANGIOSTRONGYLUS-CANTONENSIS; EQUINE MENINGOENCEPHALITIS; DIAGNOSIS; STRONGYLOIDIASIS; MENINGITIS; NEMATODA; HORSE; OSTEOMYELITIS;

D O I：

10.1128/JCM.00032-15

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H. gingivalis infection in an Australian human patient, confirmed by nematode morphology and sequencing of ribosomal DNA. The implications of this case are discussed, particularly, the need to evaluate real-time PCR as a diagnostic tool.

引用

页码：1768 / 1774

页数：7

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