Melanosome biogenesis: shedding light on the origin of an obscure organelle

被引：35

作者：

Dell'Angelica, EC ^{[1
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Human Genet, Gonda Ctr 6357B, Los Angeles, CA 90095 USA

来源：

TRENDS IN CELL BIOLOGY | 2003年 / 13卷 / 10期

关键词：

D O I：

10.1016/j.tcb.2003.08.001

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Melanosomes are specialized intracellular organelles in which melanin pigments are synthesized and stored. The ontogenesis of these morphologically unique organelles, as well as their relationship to 'conventional' organelles of the secretory and endocytic pathways, has for decades been a matter of study - and controversy. Recent work by the groups of Michael Marks and Graca Raposo has uncovered the molecular mechanism that results in the formation of the lumenal striations characteristic of melanosome precursor organelles.

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页码：503 / 506

页数：4

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