The Clinical Significance and Utility of HPV-DNA Testing in Korean Women with Atypical Glandular Cells in Cervical Pap Tests: An Analysis of 311 Cases at a Single Institution

被引：5

作者：

Jang, Tae-Kyu ^{[1
]}

Park, Jeong-Yeol ^{[2
]}

Kim, Dae-Yeon ^{[2
]}

Suh, Dae-Shik ^{[2
]}

Kim, Jong-Hyeok ^{[2
]}

Kim, Yong-Man ^{[2
]}

Kim, Young-Tak ^{[2
]}

Nam, Joo-Hyun ^{[2
]}

机构：

[1] Keimyung Univ, Donsan Med Ctr, Dept Obstet & Gynecol, Sch Med, Daegu, South Korea

[2] Univ Ulsan, Asan Med Ctr, Dept Obstet & Gynecol, Coll Med, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea

来源：

CANCER INVESTIGATION | 2021年 / 39卷 / 10期

关键词：

Atypical glandular cells; human papillomavirus; Pap test; HUMAN-PAPILLOMAVIRUS TYPES; UNDETERMINED SIGNIFICANCE; ADENOCARCINOMA; MANAGEMENT; METAANALYSIS; CYTOLOGY;

D O I：

10.1080/07357907.2021.1952593

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The aim of this study is to analyze the correlation between clinically significant histologic results and HPV in women with AGC in pap test. Of the 311 women confirmed as AGC, 111 women (35.7%) was identified as positive for HPV. In the AGC analysis, cervical lesions were significantly more common in HPV positive group compared to HPV negative group (61.2 vs. 10.5%, p < 0.001). In contrast, endometrial lesions were not associated with HPV infection (8.1 vs. 4.5%, p = 0.12). The HPV-DNA testing in women with AGC may be a useful tool for predicting clinically significant cervical lesions.

引用

页码：885 / 892

页数：8

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