BAL resin for the preparation of secondary amines

被引：16
作者：
Forns, P
Sevilla, S
Erra, M
Ortega, A
Fernández, JC
de la Figuera, N
Fernández-Forner, D
Albericio, F
机构：
[1] Almirall & Prodesfarma Barcelona Sci Pk Unit, Barcelona 08028, Spain
[2] Almirall Prodesfarma, Res Ctr, E-08024 Barcelona, Spain
[3] Barcelona Biomed Res Inst, Barcelona 08028, Spain
来源：
TETRAHEDRON LETTERS | 2003年 / 44卷 / 36期
关键词：
acidolytic cleavage; combinatorial chemistry; handle; linker; multicomponent reaction; solid-phase;
D O I：
10.1016/S0040-4039(03)01691-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Although amino acids anchored through the amino function to BAL resins can not easily be released from the resin by treatment with neat trifluoroacetic acid, we have shown that secondary amines can be obtained from BAL resins using trifluoroacetic acid solutions. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：6907 / 6910
页数：4
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