Poly(methacrylic acid)-Grafted Carbon Nanotube Scaffolds Enhance Differentiation of hESCs into Neuronal Cells

被引：55
作者：
Chao, Tzu-I [1 ]
Xiang, Shuhuai [1 ]
Lipstate, Jessica Faye [1 ]
Wang, Changchun [2 ,3 ]
Lu, Jennifer [1 ]
机构：
[1] Sch Engn, Merced, CA 95343 USA
[2] Fudan Univ, Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
[3] Fudan Univ, Adv Mat Lab, Dept Macromol Sci, Shanghai 200433, Peoples R China
来源：
ADVANCED MATERIALS | 2010年 / 22卷 / 32期
关键词：
EMBRYONIC STEM-CELLS; NEURAL DIFFERENTIATION; MOTOR-NEURONS; FUNCTIONALIZATION; PROGENITORS; BIOLOGY;
D O I：
10.1002/adma.201000262
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Poly(methacrylic acid)-grafted carbon nanotube-based thin films are found to significantly improve the neuronal differentiation efficiency, and relatively mature neuronal cells have been derived directly from hESCs, owing to their excellent protein sequestration ability and nanofibrillar characteristics. This novel material platform creates new opportunities in the tissue regeneration field.
引用
收藏
页码：3542 / +
页数：7
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