Melatonin for children with autism spectrum disorder

被引：0

作者：

Yan, Tyler ^{[1
]}

Goldman, Ran D. ^{[1
]}

机构：

[1] PRETx Program, Vancouver, BC, Canada

来源：

CANADIAN FAMILY PHYSICIAN | 2020年 / 66卷 / 03期

关键词：

PROLONGED-RELEASE MELATONIN; PHARMACOLOGICAL-TREATMENT; SLEEP; INSOMNIA; MANAGEMENT;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Question I have several patients with autism spectrum disorder (ASD) who experience difficulties with sleep, affecting the quality of life of both the child and the family. Is melatonin an effective treatment for steep problems in children with this condition? Answer Autism spectrum disorder is prevalent among children in Canada and globally, with most affected children experiencing troubles with sleep. Behavioural therapy is the first-line treatment for sleep problems in children with ASD, and melatonin has been reported to be effective and safe in this population as an alternative or adjunctive treatment. A new pediatric, prolonged-release formulation of melatonin is not yet available in Canada, but initial studies in Europe have indicated that it is a potentially effective treatment for sleep problems in children with ASD.

引用

页码：183 / 185

页数：3

共 25 条

[1] Association A.P, 2013, Diagnostic and statistical manual of mental disorders, DOI DOI 10.1176/APPI.BOOKS.9780890425596
[2] Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014
Baio, Jon
Wiggins, Lisa
Christensen, Deborah L.
Maenner, Matthew J.
Daniels, Julie
Warren, Zachary
Kurzius-Spencer, Margaret
Zahorodny, Walter
Rosenberg, Cordelia Robinson
White, Tiffany
Durkin, Maureen S.
Imm, Pamela
Nikolaou, Loizos
Yeargin-Allsopp, Marshalyn
Lee, Li-Ching
Harrington, Rebecca
Lopez, Maya
Fitzgerald, Robert T.
Hewitt, Amy
Pettygrove, Sydney
Constantino, John N.
Vehorn, Alison
Shenouda, Josephine
Hall-Lande, Jennifer
Braun, Kim Van Naarden
Dowling, Nicole F.
[J]. MMWR SURVEILLANCE SUMMARIES, 2018, 67 (06): : 1 - 23
[3] The epidemiology and global burden of autism spectrum disorders
Baxter, A. J.
Brugha, T. S.
Erskine, H. E.
Scheurer, R. W.
Vos, T.
Scott, J. G.
[J]. PSYCHOLOGICAL MEDICINE, 2015, 45 (03) : 601 - 613
[4] Controlled-release melatonin, singly and combined with cognitive behavioural therapy, for persistent insomnia in children with autism spectrum disorders: a randomized placebo-controlled trial
Cortesi, Flavia
Giannotti, Flavia
Sebastiani, Teresa
Panunzi, Sara
Valente, Donatella
[J]. JOURNAL OF SLEEP RESEARCH, 2012, 21 (06) : 700 - 709
[5] Melatonin for the management of sleep disorders in children and adolescents
Cummings, Carl
[J]. PAEDIATRICS & CHILD HEALTH, 2012, 17 (06) : 331 - 333
[6] Effectiveness of Sleep-Based Interventions for Children with Autism Spectrum Disorder: A Meta-Synthesis
Cuomo, Belinda M.
Vaz, Sharmila
Lee, Elinda Ai Lim
Thompson, Craig
Rogerson, Jessica M.
Falkmer, Torbjorn
[J]. PHARMACOTHERAPY, 2017, 37 (05): : 555 - 578
[7] Prolonged-Release Melatonin for Children With Neurodevelopmental Disorders
De Leersnyder, Helene
Zisapel, Nava
Laudon, Moshe
[J]. PEDIATRIC NEUROLOGY, 2011, 45 (01) : 23 - 26
[8] Efficacy and Safety of Pediatric Prolonged-Release Melatonin for Insomnia in Children With Autism Spectrum Disorder
Gringas, Paul
Nir, Tali
Breddy, John
Fryornan-Marom, Anat
Findling, Robert L.
[J]. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY, 2017, 56 (11) : 948 - 957
[9] Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial
Gringras, P.
Gamble, C.
Jones, A. P.
Wiggs, L.
Williamson, P. R.
Sutcliffe, A.
Montgomery, P.
Whitehouse, W. P.
Choonara, I.
Allport, T.
Edmond, A.
Appleton, R.
[J]. BRITISH MEDICAL JOURNAL, 2012, 345
[10] Health Canada, 2018, DRUGS HLTH PROD MON

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