Two new polyporusterones isolated from the sclerotia of Polyporus umbellatus

被引：21
|
作者：
Zhou, Wei-Wei
Lin, Wen-Han
Guo, Shun-Xing [1 ]
机构：
[1] Chinese Acad Med Sci, Peking Union Med Coll, Inst Med Plant Dev, Beijing 100094, Peoples R China
[2] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100083, Peoples R China
来源：
CHEMICAL & PHARMACEUTICAL BULLETIN | 2007年 / 55卷 / 08期
关键词：
polyporus umbellatus; polyporusterone; sclerotia;
D O I：
10.1248/cpb.55.1148
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In the course of searching for marker components, two new polyporusterones were isolated from the sclerotia of Polyporus umbellatus, together with another three known analogs. The structures of the new ones were elucidated as (20S,22R,24R)-16,22-epoxy-3 beta,14 alpha,23 beta,25-tetrahydroxyergost-7-en-6-one (1) and (23R,24R,25R)23,26-epoxy-3 beta,14a,21 alpha 22 alpha-tetrahydroxyergost-7-en-6-one (2) by chemical and spectroscopic means, including HR-FAB-MS, 1D- and 2D-NMR.
引用
收藏
页码：1148 / 1150
页数：3
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