Regioselective [2+2+2] cycloaddition of a nickel-benzyne complex with 1,3-diynes

被引：51
作者：
Deaton, KR [1 ]
Gin, MS [1 ]
机构：
[1] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
来源：
ORGANIC LETTERS | 2003年 / 5卷 / 14期
关键词：
D O I：
10.1021/ol034720x
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] Reactions of nickel(0)-benzyne complexes with a range of symmetrically substituted 1,3-diynes in the presence of triethylphosphine lead to the regioselective formation of 2,3-dialkynyl naphthalenes. The regioselectivity can be reversed when the diyne possesses substituents of high steric bulk, allowing selective formation of either symmetric dialkynyl naphthalene.
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页码：2477 / 2480
页数：4
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