To β-e or Not to β-e Replicating after 30: Retrospective Dating of Human Pancreatic Islets

被引:3
作者
Cobo-Vuilleumier, Nadia [1 ,2 ]
Gauthier, Benoit R. [1 ]
机构
[1] CABIMER Andalusian Ctr Mol Biol & Regenerat Med, Pancreat Islet Dev & Regenerat Unit, Dept Stem Cells, Seville 41092, Spain
[2] Hosp Carlos Haya, IMABIS Fdn, Malaga 29010, Spain
关键词
CELL MASS; EXOCRINE PANCREAS; IN-VIVO; PROLIFERATION; REGENERATION; EXPANSION; BIRTH; ENDOCRINE; PREGNANCY; APOPTOSIS;
D O I
10.1210/jc.2010-1894
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:4552 / 4554
页数:3
相关论文
共 24 条
[1]   Can β-cells be derived from exocrine pancreas? [J].
Baeyens, L. ;
Bouwens, L. .
DIABETES OBESITY & METABOLISM, 2008, 10 :170-178
[2]   A focus on the role of Pax4 in mature pancreatic islet β-cell expansion and survival in health and disease [J].
Brun, Thierry ;
Gauthier, Benoit R. .
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2008, 40 (1-2) :37-45
[3]   β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes [J].
Butler, AE ;
Janson, J ;
Bonner-Weir, S ;
Ritzel, R ;
Rizza, RA ;
Butler, PC .
DIABETES, 2003, 52 (01) :102-110
[4]   The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation [J].
Cnop, M. ;
Hughes, S. J. ;
Igoillo-Esteve, M. ;
Hoppa, M. B. ;
Sayyed, F. ;
van de Laar, L. ;
Gunter, J. H. ;
de Koning, E. J. P. ;
Walls, G. V. ;
Gray, D. W. G. ;
Johnson, P. R. V. ;
Hansen, B. C. ;
Morris, J. F. ;
Pipeleers-Marichal, M. ;
Cnop, I. ;
Clark, A. .
DIABETOLOGIA, 2010, 53 (02) :321-330
[5]   Human islet-derived precursor cells are mesenchymal stromal cells that differentiate and mature to hormone-expressing cells in vivo [J].
Davani, Behrous ;
Ikonomou, Laertis ;
Raaka, Bruce M. ;
Geras-Raaka, Elizabeth ;
Morton, Russell A. ;
Marcus-Samuels, Bernice ;
Gershengorn, Marvin C. .
STEM CELLS, 2007, 25 (12) :3215-3222
[6]   Preexisting pancreatic to acinar cell, but not islet β cell, regeneration [J].
Desai, Biva M. ;
Oliver-Krasinski, Jennifer ;
De Leon, Diva D. ;
Farzad, Cyrus ;
Hong, Nankang ;
Leach, Steven D. ;
Stoffers, Doris A. .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (04) :971-977
[7]   Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation [J].
Dor, Y ;
Brown, J ;
Martinez, OI ;
Melton, DA .
NATURE, 2004, 429 (6987) :41-46
[8]   Prevalence of diabetes complications in adolescents with type 2 compared with type 1 diabetes [J].
Eppens, Maike C. ;
Craig, Maria E. ;
Cusumano, Janine ;
Hing, Stephen ;
Chan, Albert K. F. ;
Howard, Neville J. ;
Silink, Martin ;
Donaghue, Kim C. .
DIABETES CARE, 2006, 29 (06) :1300-1306
[9]   PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression [J].
Gauthier, Benoit R. ;
Wiederkehr, Andreas ;
Baquie, Mathurin ;
Dai, Chunhua ;
Powers, Alvin C. ;
Kerr-Conte, Julie ;
Pattou, Francois ;
MacDonald, Raymond J. ;
Ferrer, Jorge ;
Wollheim, Claes B. .
CELL METABOLISM, 2009, 10 (02) :110-118
[10]   β-Cell Replication Is Increased in Donor Organs From Young Patients After Prolonged Life Support [J].
In't Veld, Peter ;
De Munch, Neelke ;
Van Belle, Kristien ;
Buelens, Nicole ;
Ling, Zhidong ;
Weets, Ilse ;
Haentjens, Patrick ;
Pipeleers-Marichal, Miriam ;
Gorus, Frans ;
Pipeleers, Daniel .
DIABETES, 2010, 59 (07) :1702-1708