Coxiella and Bartonella spp. in bats (Chiroptera) captured in the Brazilian Atlantic Forest biome

被引：48

作者：

Ferreira, Michelle Santos ^{[1
]}

Guterres, Alexandro ^{[1
]}

Rozental, Tatiana ^{[1
]}

Morim Novaes, Roberto Leonan ^{[2
]}

Vilar, Emmanuel Messias ^{[3
]}

de Oliveira, Renata Carvalho ^{[1
]}

Fernandes, Jorlan ^{[1
]}

Forneas, Danielle ^{[1
]}

Alvino Junior, Adonai ^{[1
]}

Brandao, Martha Lima ^{[4
]}

Passos Cordeiro, Jose Luis ^{[4
]}

Del Valle Alvarez, Martin Roberto ^{[5
]}

Althoff, Sergio Luiz ^{[6
]}

Moratelli, Ricardo ^{[4
]}

Cordeiro-Estrela, Pedro ^{[3
]}

da Silva, Rui Cerqueira ^{[7
]}

Sampaio de Lemos, Elba Regina ^{[1
]}

机构：

[1] Fundacao Oswaldo Cruz, Inst Oswaldo Cruz, Lab Hantaviroses & Rickettsioses, Pavilhao Helio & Peggy Pereira,1 Pavimento, Rio De Janeiro, RJ, Brazil

[2] Univ Fed Rio de Janeiro, Av Pedro Calmon,550,Cidade Univ, Rio De Janeiro, RJ, Brazil

[3] Univ Fed Paraiba, Lab Mamiferos, Dept Sistemat & Ecol, Ctr Ciencias Exatas & Nat, Campus 1, Joao Pessoa, Paraiba, Brazil

[4] Fundacao Oswaldo Cruz, Fiocruz Mata Atlantica, Estr Rodrigues Caldas 3400, Rio De Janeiro, RJ, Brazil

[5] Univ Estadual Santa Cruz, Dept Ciencias Biol, Rodovia Ilheus Itabuna,Km 16 Salobrinho, Ilheus, BA, Brazil

[6] Dcn FURB Fundacao Univ Reg Blumenau Itoupava Seca, Fundacao Univ Reg Blumenau, Dept Ciencias Nat, Ccen,Lab Biol Anim, Blumenau, SC, Brazil

[7] Univ Fed Rio de Janeiro, Lab Vertebrados, Dept Ecol, Inst Biol, Av Pedro Calmon,550,Cidade Univ, Rio De Janeiro, RJ, Brazil

来源：

BMC VETERINARY RESEARCH | 2018年 / 14卷

关键词：

Coxiella burnetii; Bartonella; Zoonotic bacterial agent; Mammals; Atlantic Forest hotspot; Brazil; MOLECULAR CHARACTERIZATION; SEQUENCE ALIGNMENT; RESERVOIR HOSTS; IDENTIFICATION; DIVERSITY; BURNETII; DISEASES; DNA;

D O I：

10.1186/s12917-018-1603-0

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Background: The role of bats as reservoirs of zoonotic agents, especially pathogenic bacteria such as Bartonella and Coxiella, has been discussed around the world. Recent studies have identified bats as potential hosts of species from the proteobacteria phylum. In Brazil, however, the role of bats in the natural cycle of these agents is poorly investigated and generally neglected. In order to analyze the participation of bats in the epidemiology of diseases caused by Bartonella, Coxiella, Rickettsia, Anaplasma and Ehrlichia, we conducted a descriptive epidemiological study in three biogeographic regions of the Brazilian Atlantic Forest. Results: Tissues of 119 bats captured in preserved areas in the states of Rio de Janeiro, Bahia and Santa Catarina from 2014 to 2015 were submitted to molecular analysis using specific primers. Bartonella spp. was detected in 22 spleen samples (18.5%, 95% CI: 11.9-26.6), whose phylogenetic analysis revealed the generation of at least two independent clusters, suggesting that these may be new unique genotypes of Bartonella species. In addition, four samples (3.4%, 95% CI: 0.9-8.3) were positive for the htpAB gene of C. burnetii [spleen (2), liver (1) and heart (1)]. Rickettsia spp., Anaplasma and Ehrlichia were not identified. This is the first study reporting C. burnetii and Bartonella spp. infections in bats from the Atlantic Forest biome. Conclusions: These findings shed light on potential host range for these bacteria, which are characterized as important zoonotic pathogens.

引用

页数：10

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