Nitric oxide photo-release from a ruthenium nitrosyl complex with a 4,4′-bisfluorenyl-2,2′-bipyridine ligand

被引：25
作者：
Roose, Max [1 ]
Sasaki, Isabelle [1 ]
Bukhanko, Valerii [1 ]
Mallet-Ladeira, Sonia [1 ]
Barba-Barba, Rodrigo M. [2 ]
Ramos-Ortiz, Gabriel [2 ]
Enriquez-Cabrera, Alejandro [3 ]
Farfan, Norberto [3 ]
Lacroix, Pascal G. [1 ]
Malfant, Isabelle [1 ]
机构：
[1] CNRS, LCC, 205 Route Narbonne,BP44099, F-31077 Toulouse 4, France
[2] CIO, AP 1-948, Leon 37000, Gto, Mexico
[3] Univ Nacl Autonoma Mexico, Fac Quim, Dept Quim Organ, Mexico City 04510, DF, Mexico
来源：
POLYHEDRON | 2018年 / 151卷
关键词：
Nitric oxide; Ruthenium complexes; Two-photon absorption; Photochemistry; DFT computations; 2-PHOTON PHOTODYNAMIC THERAPY; DINITROSYL IRON COMPLEXES; SENSITIZED SOLAR-CELLS; MANGANESE NITROSYL; SINGLET OXYGEN; BIOLOGICAL-ACTIVITY; BIPYRIDINE LIGAND; TARGETED DELIVERY; ELECTRON-TRANSFER; NO-RELEASE;
D O I：
10.1016/j.poly.2018.05.028
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A ruthenium nitrosyl complex of formula [Ru-II(terpy)(F2B)(NO)](PF6)(3), where terpy stands for 2,2':6',2-terpyridine and F2B for 4,4'-bis(9,9'-dibutyl-9H-fluoren-2-yl)-2,2'-bipyridine, is presented and fully characterized. The X-ray crystal structure of F2B is reported. The electronic properties of the complex are compared to those of related [Ru-II(terpy)(bpy)(NO)](3+) complexes having a bipyridine (bpy) free of fluorene or bearing a fluorene on the terpyridine ligand. DFT computations are provided to support the experimental data. [Ru-II(terpy)(F2B)(NO)](PF6)(3) releases NO under irradiation at 405 nm with a quantum yield (phi(NO)) equal to 0.033. Additionally, the two-photon absorption cross-section investigated at 800 nm by the Z-scan technics is equal to 156 +/- 23GM, which indicates that the complex can release NO under irradiation in the therapeutic window. (C) 2018 Elsevier Ltd. All rights reserved.
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页码：100 / 111
页数：12
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