Orthogonal ligation to spherical polymeric microparticles: Modular approaches for surface tailoring

被引:49
作者
Goldmann, Anja S. [1 ]
Barner, Leonie [2 ]
Kaupp, Michael [1 ]
Vogt, Andrew P. [1 ]
Barner-Kowollik, Christopher [1 ]
机构
[1] Karlsruhe Inst Technol KIT, Inst Tech Chem & Polymerchem, D-76128 Karlsruhe, Germany
[2] Fraunhofer Inst Chem Technol, D-76327 Pfinztal, Germany
关键词
Polymeric microparticles; Grafting-to; Surface functionalization; Orthogonal modification; Click chemistry; MONODISPERSE POLY(DIVINYLBENZENE) MICROSPHERES; CLICK CHEMISTRY; THIOL-ENE; PRECIPITATION POLYMERIZATION; SUSPENSION POLYMERIZATION; MAGNETIC MICROSPHERES; POLYETHYLENE-GLYCOL; JANUS PARTICLES; FUNCTIONALIZATION; IMMOBILIZATION;
D O I
10.1016/j.progpolymsci.2011.11.008
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Modular ligation strategies for the functionalization of polymeric microspheres provide new perspectives for their applications in material science. In the current trend article we highlight variable synthetic procedures for generating functional microspheres via orthogonal modular conjugation chemistries. An overview of the different surface chemistries available is provided, followed by surface-sensitive characterization techniques relevant for the microparticles. Finally, we explore future trends in modular orthogonal modification approaches on microparticles and provide an outlook on the perspectives that the field of surface-modification of polymeric microparticles holds. (C) 2011 Elsevier Ltd. All rights reserved.
引用
收藏
页码:975 / 984
页数:10
相关论文
共 84 条
  • [1] Arica MY, 2005, POLYM INT, V54, P153, DOI 10.1002/pi.1662
  • [3] Monodisperse poly(p-chloromethylstyrene) microbeads by dispersion polymerization
    Bahar, T
    Tuncel, A
    [J]. POLYMER ENGINEERING AND SCIENCE, 1999, 39 (10) : 1849 - 1855
  • [4] Synthesis of narrow or monodisperse poly(divinylbenzene) microspheres by distillation-precipitation polymerization
    Bai, F
    Yang, XL
    Huang, WQ
    [J]. MACROMOLECULES, 2004, 37 (26) : 9746 - 9752
  • [5] Synthesis of core-shell poly(divinylbenzene) microspheres via reversible addition fragmentation chain transfer graft polymerization of styrene
    Barner, L
    Li, C
    Hao, XJ
    Stenzel, MH
    Barner-Kowollik, C
    Davis, TP
    [J]. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2004, 42 (20) : 5067 - 5076
  • [6] Synthesis of Microspheres as Versatile Functional Scaffolds for Materials Science Applications
    Barner, Leonie
    [J]. ADVANCED MATERIALS, 2009, 21 (24) : 2547 - 2553
  • [7] "Clicking" Polymers or Just Efficient Linking: What Is the Difference?
    Barner-Kowollik, Christopher
    Du Prez, Filip E.
    Espeel, Pieter
    Hawker, Craig J.
    Junkers, Tanja
    Schlaad, Helmut
    Van Camp, Wim
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (01) : 60 - 62
  • [8] Towards Designer Microparticles: Simultaneous Control of Anisotropy, Shape, and Size
    Bhaskar, Srijanani
    Pollock, Kelly Marie
    Yoshida, Mutsumi
    Lahann, Joerg
    [J]. SMALL, 2010, 6 (03) : 404 - 411
  • [9] Bioinspired design and assembly of platelet reinforced polymer films
    Bonderer, Lorenz J.
    Studart, Andre R.
    Gauckler, Ludwig J.
    [J]. SCIENCE, 2008, 319 (5866) : 1069 - 1073
  • [10] Functionalization of Polymer Microspheres Using Click Chemistry
    Breed, Dana R.
    Thibault, Raymond
    Xie, Fang
    Wang, Qian
    Hawker, Craig J.
    Pine, David J.
    [J]. LANGMUIR, 2009, 25 (08) : 4370 - 4376