Palladium-Catalyzed Direct C-H Bond Alkynylations of Heteroarenes Using gem-Dichloroalkenes

被引：49

作者：

Ackermann, Lutz ^{[1
]}

Kornhaass, Christoph ^{[1
]}

Zhu, Yingjun ^{[1
]}

机构：

[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany

来源：

ORGANIC LETTERS | 2012年 / 14卷 / 07期

关键词：

DIRECT ARYLATIONS; ARYL CHLORIDES; COPPER; HETEROCYCLES; ACTIVATION; 1,3,4-OXADIAZOLES; BENZYLATIONS; CONSTRUCTION; PRELIGANDS; PARTNERS;

D O I：

10.1021/ol300514d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed direct alkynylations of heteroarenes were accomplished with inexpensive gem-dichloroalkenes as user-friendly electrophiles, which set the stage for a modular, step-economical synthesis of diversely decorated heteroaryl alkynes with ample scope.

引用

页码：1824 / 1826

页数：3

共 61 条

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