Phase composition and in vitro bioactivity of porous implants made of bioactive glass S53P4

被引：41

作者：

Fagerlund, S. ^{[1
]}

Massera, J. ^{[1
]}

Moritz, N. ^{[2
]}

Hupa, L. ^{[1
]}

Hupa, M. ^{[1
]}

机构：

[1] Abo Akad Univ, Proc Chem Ctr, FI-20500 Turku, Finland

[2] Univ Turku, Dept Orthopaed Surg & Traumatol, Orthopaed Res Unit, FI-20520 Turku, Finland

来源：

ACTA BIOMATERIALIA | 2012年 / 8卷 / 06期

基金：

芬兰科学院;

关键词：

S53P4; Bioactive glass; Sintering; In vitro; BONE-GRAFT SUBSTITUTES; CHEMICAL-PROPERTIES; CERAMIC SCAFFOLDS; AUTOGENOUS BONE; 45S5; CRYSTALLIZATION; BEHAVIOR; TISSUE; TEMPERATURE; SYSTEM;

D O I：

10.1016/j.actbio.2012.03.011

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This work studied the influence of sintering temperature on the phase composition, compression strength and in vitro properties of implants made of bioactive glass S53P4. The implants were sintered within the temperature range 600-1000 degrees c. Over the whole temperature range studied, consolidation took place mainly via viscous flow sintering, even though there was partial surface crystallization. The mechanical strength of the implants was low but increased with the sintering temperature, from 0.7 MPa at 635 degrees C to 10 MPa at 1000 degrees C. Changes in the composition of simulated body fluid (SBF), the immersion solution, were evaluated by pH measurements and ion analysis using inductively coupled plasma optical emission spectrometry. The development of a calcium phosphate layer on the implant surfaces was verified using scanning electron microscopy-electron-dispersive X-ray analysis. When immersed in SBF, a calcium phosphate layer formed on all the samples, but the structure of this layer was affected by the surface crystalline phases. Hydroxyapatite formed more readily on amorphous and partially crystalline implants containing both primary Na2O center dot CaO center dot 2SiO(2) and secondary Na2Ca4(PO4)(2)SiO4 crystals than on implants containing only primary crystals. (C) 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：2331 / 2339

页数：9

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