HMDS-promoted in situ amidation reactions of carboxylic acids and amines

被引：22

作者：

Chou, WC ^{[1
]}

Chou, MC ^{[1
]}

Lu, YY ^{[1
]}

Chen, SF ^{[1
]}

机构：

[1] Dev Ctr Biotechnol, Pharmaceut R&D Labs, Nat Prod & Med Chem, Yokohama, Kanagawa 221, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(99)00505-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A number of N-acylalkylenediamines were synthesized in high yields by in situ monoamidation of carboxylic acids with diamines. The amidation reactions were carried out simply by heating the substrates at 110 degrees C for 5-24 h in the presence of HMDS. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：3419 / 3422

页数：4

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