Fluorophore and protein conjugated Diels-Alder functionalized CVD graphene layers

被引：7

作者：

Chang, Huai-Ning ^{[1
,2
]}

Sarkar, Santanu ^{[3
,4
]}

Baker, James R., Jr. ^{[2
]}

Norris, Theodore B. ^{[5
]}

机构：

[1] Univ Michigan, Biomed Engn, Ann Arbor, MI 48109 USA

[2] Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA

[3] Univ Calif Riverside, Ctr Nanoscale Sci & Engn, Dept Chem, Riverside, CA 92521 USA

[4] Univ Calif Riverside, Ctr Nanoscale Sci & Engn, Dept Chem & Environm Engn, Riverside, CA 92521 USA

[5] Univ Michigan, Ctr Photon & Multiscale Nanomat, Ann Arbor, MI 48109 USA

来源：

OPTICAL MATERIALS EXPRESS | 2016年 / 6卷 / 10期

基金：

美国国家科学基金会;

关键词：

RAMAN-SPECTROSCOPY; CARBON NANOTUBES; CHEMISTRY; COVALENT; IMMOBILIZATION; BIOSENSORS; GRAPHITE; SURFACES; POINT;

D O I：

10.1364/OME.6.003242

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Chemical modification of the graphene is emerging as a promising approach in producing graphene devices for electronics and nano/biotechnology applications. The electronic and chemical properties of graphene can be modified by Diels-Alder chemistry via formation of sp(3) centers on the graphene lattice. Here we develop an approach of creating -COOH functional groups on CVD graphene using Diels-Alder reaction with hydrolysis. Conventionally, -COOH functional groups on graphene was often created using graphene oxide. In our approach, we functionalized a CVD graphene sheet and -COOH groups can be conjugated to fluorophores and proteins. This allows visualization of a graphene layer and estimation of functional group density using XPS with efficiency and convenience. (C)2016 Optical Society of America

引用

页码：3242 / 3253

页数：12

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