Basilar artery occlusion

被引:485
|
作者
Mattle, Heinrich P. [1 ]
Arnold, Marcel [1 ]
Lindsberg, Perttu J. [3 ,4 ]
Schonewille, Wouter J. [5 ,6 ]
Schroth, Gerhard [2 ]
机构
[1] Univ Bern, Inselspital, Dept Neurol, CH-3010 Bern, Switzerland
[2] Univ Bern, Inselspital, Dept Diagnost & Intervent Neuroradiol, CH-3010 Bern, Switzerland
[3] Univ Helsinki, Cent Hosp, Dept Neurol, Helsinki, Finland
[4] Univ Helsinki, Biomedicum Helsinki, Res Programs Unit, Helsinki, Finland
[5] St Antonius Hosp, Dept Neurol, Nieuwegein, Netherlands
[6] Univ Med Ctr Utrecht, Utrecht, Netherlands
关键词
ACUTE ISCHEMIC-STROKE; LOCKED-IN-SYNDROME; ACUTE VERTEBROBASILAR OCCLUSION; CEREBRAL-BLOOD-FLOW; MECHANICAL THROMBECTOMY; INTERNATIONAL-COOPERATION; INTRAVENOUS THROMBOLYSIS; LOCAL FIBRINOLYSIS; EVOKED-POTENTIALS; BRAIN-STEM;
D O I
10.1016/S1474-4422(11)70229-0
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The clinical presentation of basilar artery occlusion (BAO) ranges from mild transient symptoms to devastating strokes with high fatality and morbidity. Often, non-specific prodromal symptoms such as vertigo or headaches are indicative of BAO, and are followed by the hallmarks of BAO, including decreased consciousness, quadriparesis, pupillary and oculomotor abnormalities, dysarthria, and dysphagia. When clinical findings suggest an acute brainstem disorder, BAO has to be confirmed or ruled out as a matter of urgency. If BAO is recognised early and confirmed with multimodal CT or Mill, intravenous thrombolysis or endovascular treatment can be undertaken. The goal of thrombolysis is to restore blood flow in the occluded artery and salvage brain tissue; however, the best treatment approach to improve clinical outcome still needs to be ascertained.
引用
收藏
页码:1002 / 1014
页数:13
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