Paralytic shellfish poisoning toxin profile of mussels Perna perna from southern Atlantic coasts of Morocco

被引：11

作者：

Abouabdellah, Rachid ^{[1
]}

Taleb, Hamid ^{[3
]}

Bennouna, Asmae ^{[1
]}

Erler, Katrin ^{[4
]}

Chafik, Abdeghani ^{[3
]}

Moukrim, Abdelatif ^{[2
]}

机构：

[1] Inst Natl Rech Halieut, Agadir, Morocco

[2] Univ Ibnou Zohr, Fac Sci Ibnou Zohr, Agadir, Morocco

[3] Inst Natl Rech Halieut, Casablanca, Morocco

[4] Univ Jena, D-07743 Jena, Germany

来源：

TOXICON | 2008年 / 51卷 / 05期

关键词：

Alexandrium minutum; paralytic shellfish poisoning; toxin profile; Perna perna; Morocco;

D O I：

10.1016/j.toxicon.2007.12.004

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

During the monitoring programme of harmful algal blooms established along the south Atlantic coast of Morocco, a bimonthly determination of harmful algae and phycotoxins analysis in Perna perna was carried out from May 2003 to December 2004. Results of mouse bioassay (in organs and whole flesh) showed a seasonal evolution of paralytic shellfish poisoning (PSP) toxin. The mussel's contamination was associated with the occurrence in water of Alexandrium minutum. The PSP toxin profile obtained with high-performance liquid chromatography (HPLC/FD) revealed the dominance of gonyautoxins GTX2 and GTX3 and a minority of GTX1, GTX4 and saxitoxin (STX). This profile explains that the toxicity was mainly associated with A. minutum. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：780 / 786

页数：7

共 7 条

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Taleb, H
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TOXICON, 2001, 39 (12) : 1855 - 1861
[2] USE OF A LIQUID CHROMATOGRAPHIC METHOD FOR ASSESSMENT OF PARALYTIC SHELLFISH POISONING TOXIN PROFILES IN MUSSELS AND CLAMS FROM URUGUAY
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