Asymptomatic Leishmania infantum/chagasi infection in blood donors of western Sicily

被引：38

作者：

Scarlata, Francesco ^{[1
]}

Vitale, Fabrizio ^{[2
]}

Saporito, Laura ^{[1
]}

Reale, Stefano ^{[2
]}

Vecchi, Valentina Li ^{[1
]}

Giordano, Salvatore ^{[1
]}

Infurnari, Laura ^{[1
]}

Occhipinti, Francesco ^{[3
]}

Titone, Lucina ^{[1
]}

机构：

[1] Univ Palermo, Ist Patol Infettiva & Virol, I-90129 Palermo, Italy

[2] Ist Zooprofilattico Sperimentale Sicilia, I-90100 Palermo, Italy

[3] UO Med Trasfusionale, Osped San Giovanni Dio, I-92100 Agrigento, Italy

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2008年 / 102卷 / 04期

关键词：

Leishmania; parasitemia; asymptomatic infections; blood donors; blood transfusion; Italy;

D O I：

10.1016/j.trstmh.2008.01.011

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The purpose of this study was to evaluate whether the risk of transfusion-transmitted visceral leishmaniasis was present in an area of western Sicily where the incidence of the disease is higher than the regional average. From May to December 2005, 1449 blood donors from Agrigento district (Sicily, Italy) were screened for the presence of anti-Leishmania antibodies by an indirect immunofluorescent antibody test (IFAT). Blood samples from IFAT-positive donors were examined by PCR to detect Leishmania DNA. Anti-Leishmania antibodies were found in 11 (0.75%) cases, among which Leishmania DNA was detected from four (36.4%). Particular techniques to inactivate different pathogens would be considered mandatory in the case of immunosuppressed recipients. (c) 2008 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

引用

页码：394 / 396

页数：3

共 10 条

[1]

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