Transforming growth factor β2 increases in subretinal fluid in rhegmatogenous retinal detachment with subretinal strands

被引：12
|
作者：
Hirase, K
Sugiyama, T
Ikeda, T
Sotozono, C
Yasuhara, T
Koizumi, K
Kinoshita, S
机构：
[1] Osaka Med Coll, Dept Ophthalmol, Takatsuki, Osaka 5698686, Japan
[2] Kyoto Prefectural Univ Med, Dept Ophthalmol, Kyoto, Japan
来源：
OPHTHALMOLOGICA | 2005年 / 219卷 / 04期
关键词：
transforming growth factor beta(2); rhegmatogenous retinal detachment; subretinal fluid; subretinal strand;
D O I：
10.1159/000085731
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose: To compare transforming growth factor (TGF) beta(2) levels in subretinal fluid of rhegmatogenous retinal detachment with or without subretinal strand formation. Methods: We assessed total and mature TGF-beta(2) levels in subretinal fluid obtained from 24 eyes with rhegmatogenous retinal detachment using an enzyme-linked immunosorbent assay. Group I comprised 18 specimens from eyes without subretinal strands, while group II comprised 6 specimens from eyes with subretinal strands. Results: Total and mature TGF-beta(2) levels were higher in group II than in group I (p = 0.01 and p = 0.07, respectively). Conclusion: The concentrations of total and mature TGF-beta(2) were higher in cases of rhegmatogenous retinal detachment associated with subretinal strand formation compared to those without subretinal strand formation. (C) 2005 S. Karger AG, Basel.
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收藏
页码：222 / 225
页数：4
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