Assessment of tear-evaporation rate in thyroid-gland patients

被引:26
作者
Abusharaha, Ali [1 ]
Alturki, Abdulaziz A. [1 ]
Alanazi, Saud A. [1 ]
Fagehi, Raied [1 ]
Al-Johani, Naji [2 ]
El-Hiti, Gamal A. [1 ]
Masmali, Ali M. [1 ]
机构
[1] King Saud Univ, Coll Appl Med Sci, Dept Optometry, POB 10219, Riyadh 11433, Saudi Arabia
[2] King Fahad Med City, Comprehens Canc Ctr, Dept Endocrinol & Thyroid Oncol, Riyadh 11433, Saudi Arabia
关键词
thyroid gland; thyroid-associated ophthahnopathy; Graves's ophthahnopathy; dry eye; tear-evaporation rate; evaporative dry eye; DRY EYE DISEASE; NORMAL ADULTS; HYPOTHYROIDISM; REPEATABILITY; OSMOLARITY; PHYSIOLOGY; DIAGNOSIS; SYSTEM;
D O I
10.2147/OPTH.S188614
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Objective: To assess the tear-evaporation rate in thyroid-gland patients using a VapoMeter. Methods: Twenty- thyroid gland patients aged 18-43 years (mean 34.3 +/- 6.3 years) completed the study. Additionally, an age-matched control group of 20 patients aged 18-43 years (32.2 +/- 5.1 years) was enrolled in the study for comparison purposes. An Ocular Surface Disease Index dry-eye questionnaire was completed, followed by a test to deterinine the tear-evaporation rate using the VapoMeter. The test was performed three times per subject by the same examiner. Two readings were obtained each time. Results: Significant differences (P<0.05) were found between mean Ocular Surface Disease Index and tear-evaporation-rate scores within the study and control groups. The average tear-evaporation rate was much higher in the study group (median 41.2 [I(21( 41.4] g/m(2).h) than the control group (15.7 [13.7] g/m(2).1). Moreover, the average Ocular Surface Disease Index score for thyroid-gland patients was much higher (15.6 [23.4]) compared to the control group (5.5 [7.50]). Conclusion: The v, poration rate in thyroid-gland patients was found to be much higher than normal-eye subjects.
引用
收藏
页码:131 / 135
页数:5
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