An efficient approach to pyrazolo[5,1-a]isoquinolin-2-amines via a silver(I)-catalyzed three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and nitrile

被引：24
作者：
Yu, Xingxin [3 ]
Yang, Qin [1 ,2 ]
Lou, Honglei [3 ]
Peng, Yiyuan [1 ,2 ]
Wu, Jie [3 ]
机构：
[1] Jiangxi Normal Univ, Minist Educ, Key Lab Funct Small Organ Mol, Nanchang 330022, Jiangxi, Peoples R China
[2] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China
[3] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2011年 / 9卷 / 20期
基金：
中国国家自然科学基金;
关键词：
PLATELET-ACTIVATING-FACTOR; DNA-BINDING AGENTS; MULTICOMPONENT REACTIONS; ORGANIC-SYNTHESIS; TANDEM REACTION; CHEMISTRY; TRANSFORMATIONS; STRATEGIES; DISCOVERY;
D O I：
10.1039/c1ob05917c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A three-component reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and nitrile catalyzed by silver triflate under mild conditions is reported, which generates pyrazolo[5,1-a]isoquinolin-2-amines in good to excellent yields.
引用
收藏
页码：7033 / 7037
页数：5
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