Updated multiplex polymerase chain reaction for detection of 16S rRNA methylases: high prevalence among NDM-1 producers

被引：87
作者：
Bercot, Beatrice [1 ,2 ]
Poirel, Laurent [1 ]
Nordmann, Patrice [1 ]
机构：
[1] Univ Paris 11, Fac Med Paris Sud, Hop Bicetre,Serv Bacteriol Virol, AP HP,INSERM Emerging Resistance Antibiot U914, F-94275 K Bicetre, France
[2] Univ Paris 07, Hop Lariboisiere, Serv Bacteriol Virol Hyg, Paris, France
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2011年 / 71卷 / 04期
关键词：
16S rRNA methylase; Multiplex PCR; NDM-1; LACTAMASE-PRODUCING ENTEROBACTERIACEAE; ESCHERICHIA-COLI; RESISTANCE;
D O I：
10.1016/j.diagmicrobio.2011.08.016
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We develop a rapid (<4 h) and reliable multiplex polymerase chain reaction for screening of 16S rRNA methylase genes conferring resistance to aminoglycosides. This study particularly underlined that 16S rRNA methylases are frequently (75%) identified among Enterobacteriaceae isolates producing the carbapenemase NDM-1. (C) 2011 Elsevier Inc. All rights reserved.
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收藏
页码：442 / 445
页数：4
相关论文
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