Influence of HMPA on reducing power and reactivity of SmBr2

被引：55

作者：

Knettle, BW ^{[1
]}

Flowers, RA ^{[1
]}

机构：

[1] Univ Toledo, Dept Chem, Toledo, OH 43606 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 15期

关键词：

D O I：

10.1021/ol0160957

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Addition of HMPA to SmBr2 in THF produces a reactant with an estimated redox potential of -2.63 +/- 0.01 V (vs AS/AgNO3), This powerful reductant is capable of reducing ketimines and alkyl chlorides at room temperature. Although the structure of the reductant has not been established, it is nonetheless a powerful addition to the arsenal of samarium based reductants currently utilized.

引用

页码：2321 / 2324

页数：4

共 23 条

[1] Samarium-induced iodine-catalyzed reduction of imines: synthesis of amine derivatives [J].