Design, fabrication and characterization of PCL electrospun scaffolds-a review

被引：503

作者：

Cipitria, A. ^{[1
,2
,3
]}

Skelton, A. ^{[1
]}

Dargaville, T. R. ^{[1
]}

Dalton, P. D. ^{[1
,4
]}

Hutmacher, D. W. ^{[1
,5
]}

机构：

[1] Queensland Univ Technol, Inst Hlth & Biomed Innovat, Brisbane, Qld 4059, Australia

[2] Charite, Ctr Musculoskeletal Surg, Berlin Brandenburg Ctr Regenerat Therapies, D-13353 Berlin, Germany

[3] Charite, Julius Wolff Inst, D-13353 Berlin, Germany

[4] Shanghai Jiao Tong Univ, Med Res Inst X, Shanghai 200030, Peoples R China

[5] Georgia Inst Technol, George W Woodruff Sch Mech Engn, Atlanta, GA 30332 USA

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2011年 / 21卷 / 26期

基金：

澳大利亚研究理事会;

关键词：

MESENCHYMAL STEM-CELLS; BIODEGRADABLE NANOFIBROUS SCAFFOLDS; POLYMER SURFACE MODIFICATION; HUMAN DERMAL FIBROBLASTS; HUMAN-ENDOTHELIAL CELLS; IN-VIVO DEGRADATION; EXTRACELLULAR-MATRIX; MECHANICAL-PROPERTIES; POLYCAPROLACTONE SCAFFOLDS; OSTEOGENIC DIFFERENTIATION;

D O I：

10.1039/c0jm04502k

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The expanding interest in electrospinning fibers for bioengineering includes a significant use of polyesters, including poly(epsilon-caprolactone) (PCL). This review summarizes literature on PCL and selected blends, and provides extensive descriptions of the broad range of parameters used in manufacturing such electrospun fibers. Furthermore the chemical, physical and biological approaches for characterizing the electrospun material are described and opinions offered on important information to include in future publications with this electrospun material.

引用

页码：9419 / 9453

页数：35

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