Hepatopulmonary syndrome: An update

被引：12

作者：

Gandhi, Kejal D. ^{[1
]}

Taweesedt, Pahnwat Tonya ^{[2
]}

Sharma, Munish ^{[2
]}

Surani, Salim ^{[3
,4
]}

机构：

[1] Georgetown Univ, Medstar Washington Hosp Ctr, Dept Internal Med, Washigton, DC 20010 USA

[2] Corpus Christi Med Ctr, Dept Med, Corpus Christi, TX 78412 USA

[3] Texas A&M Univ, Dept Med, 8447 Riverside Pkwy, Bryan, TX 78413 USA

[4] Mayo Clin, Dept Anesthesiol, Rochester, MN 55905 USA

来源：

WORLD JOURNAL OF HEPATOLOGY | 2021年 / 13卷 / 11期

关键词：

Hepatopulmonary syndrome; Chronic liver disease; Hypoxemia; Intrapulmonary vasodilatation; Liver failure; VENTILATION-PERFUSION RELATIONSHIPS; INTRAHEPATIC PORTOSYSTEMIC SHUNT; EXHALED NITRIC-OXIDE; LIVER-TRANSPLANTATION; GAS-EXCHANGE; CONTRAST ECHOCARDIOGRAPHY; CIRRHOTIC-PATIENTS; PENTOXIFYLLINE; SURVIVAL; ABNORMALITIES;

D O I：

10.4254/wjh.v13.i11.1699

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatopulmonary syndrome (HPS) is characterized by defects in oxygenation caused by intra-pulmonary vasodilation occurring because of chronic liver disease, portal hypertension, or congenital portosystemic shunts. Clinical implications of portal hypertension are very well-known, however, awareness of its effect on multiple organs such as the lungs are less known. The presence of HPS in chronic liver disease is associated with increased mortality. Medical therapies available for HPS have not been proven effective and definitive treatment for HPS is mainly liver transplantation (LT). LT improves mortality for patients with HPS drastically. This article provides a review on the definition, clinical presentation, diagnosis, and management of HPS.

引用

页码：1699 / 1706

页数：8

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