Gadolinium-doped magnetite nanoparticles from a single-source precursor

被引：37

作者：

Douglas, F. J. ^{[1
]}

MacLaren, D. A. ^{[2
]}

Maclean, N. ^{[1
]}

Andreu, I. ^{[3
]}

Kettles, F. J. ^{[1
]}

Tuna, F. ^{[4
]}

Berry, C. C. ^{[5
]}

Castro, M. ^{[3
]}

Murrie, M. ^{[1
]}

机构：

[1] Univ Glasgow, Sch Chem, WestCHEM, Glasgow G12 8QQ, Lanark, Scotland

[2] Univ Glasgow, Sch Phys & Astron, SUPA, Glasgow G12 8QQ, Lanark, Scotland

[3] Univ Zaragoza, CSIC, ICMA, Campus Rio Ebro,Maria de Luna 3, Zaragoza 50018, Spain

[4] Univ Manchester, Natl EPR Ctr, Oxford Rd, Manchester M13 9PL, Lancs, England

[5] Univ Glasgow, CMVLS, Ctr Cell Engn, Glasgow G12 8QQ, Lanark, Scotland

来源：

RSC ADVANCES | 2016年 / 6卷 / 78期

基金：

英国工程与自然科学研究理事会;

关键词：

IRON-OXIDE NANOPARTICLES; DUAL-MODAL MRI; THERMAL-DECOMPOSITION; CONTRAST AGENTS; GD; SHAPE; T-1;

D O I：

10.1039/c6ra18095g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An iron and gadolinium-containing bimetallic polynuclear complex was used as a single source precursor in the synthesis of gadolinium-doped magnetite nanoparticles (Gd:Fe3O4). The synthesis produces well defined octahedral particles (12.6 +/- 2.6 nm diameter) with a gadolinium content in the region of 2 mol%. The nanoparticles showed a value of the specific absorption rate of 3.7 +/- 0.6 W g(Fe)(-1) under low-amplitude radiofrequency magnetic field excitation, and moderate biocompatibility, suggesting that these particles are viable candidates for magnetic hyperthermia applications.

引用

页码：74500 / 74505

页数：6

共 42 条

[1] Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia [J].

Andreu, Irene ;

Natividad, Eva ;

Solozabal, Laura ;

Roubeau, Olivier .

ACS NANO, 2015, 9 (02) :1408-1419

[2] Synthesis of magnetite nanoparticles by thermal decomposition of ferrous oxalate dihydrate [J].

Angermann, Andre ;

Toepfer, Joerg .

JOURNAL OF MATERIALS SCIENCE, 2008, 43 (15) :5123-5130

[3] Bioinspired Synthesis and Characterization of Gadolinium-Labeled Magnetite Nanoparticles for Dual Contrast T1- and T2-Weighted Magnetic Resonance Imaging [J].

Bae, Ki Hyun ;

Kim, Young Beom ;

Lee, Yuhan ;

Hwang, JinYoung ;

Park, HyunWook ;

Park, Tae Gwan .

BIOCONJUGATE CHEMISTRY, 2010, 21 (03) :505-512

[4] Possible exploitation of magnetic nanoparticle-cell interaction for biomedical applications [J].

Berry, CC .

JOURNAL OF MATERIALS CHEMISTRY, 2005, 15 (05) :543-547

[5] Simple models for dynamic hysteresis loop calculations of magnetic single-domain nanoparticles: Application to magnetic hyperthermia optimization [J].

Carrey, J. ;

Mehdaoui, B. ;

Respaud, M. .

JOURNAL OF APPLIED PHYSICS, 2011, 109 (08)

[6] Inhomogeneous composition of alloyed iron-platinum magnetic nanoparticles synthesized at low temperature [J].

Chen, Shu ;

MacLaren, Donald A. ;

Baker, Richard T. ;

Chapman, John N. ;

Lee, Stephen ;

Cole-Hamilton, David J. ;

Andre, Pascal .

JOURNAL OF MATERIALS CHEMISTRY, 2011, 21 (11) :3646-3654

[7]

Cortajarena Aitziber L, 2014, Nanobiomedicine (Rij), V1, P2, DOI 10.5772/58841

[8]

Douglas F. J., 2012, THESIS

[9] Formation of octapod MnO nanoparticles with enhanced magnetic properties through kinetically-controlled thermal decomposition of polynuclear manganese complexes [J].

Douglas, Fraser J. ;

MacLaren, Donald A. ;

Tuna, Floriana ;

Holmes, William M. ;

Berry, Catherine C. ;

Murrie, Mark .

NANOSCALE, 2014, 6 (01) :172-176

[10] A study of the role of the solvent during magnetite nanoparticle synthesis: tuning size, shape and self-assembly [J].

Douglas, Fraser J. ;

MacLaren, Donald A. ;

Murrie, Mark .

RSC ADVANCES, 2012, 2 (21) :8027-8035

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