Factor Xa Inhibition Prevents Cardiac Remodeling Induced by Intermittent Hypoxia in Sleep Apnea Model Mice

被引:0
|
作者
Yoshimura, Fumi
Tanikawa, Shota
Hosako, Shogo
Kato, Ryuji
Ijiri, Yoshio
Izumi, Yasukatsu
Yoshiyama, Minoru
Hayashi, Tetsuya
机构
关键词
rivaroxaban; hypoxia; cardiac remodeling; oxidative stress; ultrastructure;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
13846
引用
收藏
页数:4
相关论文
共 50 条
  • [31] The antioxidant α-lipoic acid attenuates intermittent hypoxia-related renal injury in a mouse model of sleep apnea
    Abuyassin, Bisher
    Badran, Mohammad
    Ayas, Najib T.
    Laher, Ismail
    SLEEP, 2019, 42 (06)
  • [32] Alpha adrenergic receptor signaling in the hypothalamic paraventricular nucleus is diminished by the chronic intermittent hypoxia model of sleep apnea
    Domingos-Souza, Gean
    Martinez, Diana
    Sinkler, Steven
    Heesch, Cheryl M.
    Kline, David D.
    EXPERIMENTAL NEUROLOGY, 2021, 335
  • [33] Late-breaking abstract: Intermittent hypoxia alters gut microbiota diversity in a mouse model of sleep apnea
    Queipo-Ortuno, M. I.
    Moreno-Indias, I.
    Torres, M.
    Montserrat, J. M.
    Sanchez-Alcoholado, L.
    Cardona, F.
    Farre, R.
    EUROPEAN RESPIRATORY JOURNAL, 2014, 44
  • [34] Spatial learning and memory deficits following exposure to 24 h of sleep fragmentation or intermittent hypoxia in a rat model of obstructive sleep apnea
    Ward, Christopher P.
    McCoy, John G.
    McKenna, James T.
    Connolly, Nina P.
    McCarley, Robert W.
    Strecker, Robert E.
    BRAIN RESEARCH, 2009, 1294 : 128 - 137
  • [35] Metallothionein prevents intermittent hypoxia-induced cardiac endoplasmic reticulum stress and cell death likely via activation of Akt signaling pathway in mice
    Zhou, Shansha
    Yin, Xia
    Zheng, Yang
    Miao, Xiao
    Feng, Wenke
    Cai, Jun
    Cai, Lu
    TOXICOLOGY LETTERS, 2014, 227 (02) : 113 - 123
  • [36] Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice
    Takatoshi Nakagawa
    Yuichi Furukawa
    Tetsuya Hayashi
    Atsuo Nomura
    Shunichi Yokoe
    Kazumasa Moriwaki
    Ryuji Kato
    Yoshio Ijiri
    Takehiro Yamaguchi
    Yasukatsu Izumi
    Minoru Yoshiyama
    Michio Asahi
    Hypertension Research, 2019, 42 : 1858 - 1871
  • [37] Augmented O-GlcNAcylation attenuates intermittent hypoxia-induced cardiac remodeling through the suppression of NFAT and NF-κB activities in mice
    Nakagawa, Takatoshi
    Furukawa, Yuichi
    Hayashi, Tetsuya
    Nomura, Atsuo
    Yokoe, Shunichi
    Moriwaki, Kazumasa
    Kato, Ryuji
    Ijiri, Yoshio
    Yamaguchi, Takehiro
    Izumi, Yasukatsu
    Yoshiyama, Minoru
    Asahi, Michio
    HYPERTENSION RESEARCH, 2019, 42 (12) : 1858 - 1871
  • [38] Chronic intermittent hypoxia accelerates cardiac dysfunction and cardiac remodeling during cardiac pressure overload in mice and can be alleviated by PHD3 overexpression
    Xu, Xuan
    Zhen, Peng-Hao
    Yu, Fu-Chao
    Wang, Tao
    Li, Sheng-Nan
    Wei, Qin
    Tong, Jia-Yi
    FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9
  • [39] Lr11 Gene Deficiency Prevents Hypoxia-induced Pulmonary Hypertension and Vascular Remodeling in Mice
    Jiang, Le
    Konishi, Hakuoh
    Jiang, Meizi
    Bujo, Hideaki
    Daida, Hiroyuki
    CIRCULATION, 2014, 130
  • [40] Tissue Oxygenation in Brain, Muscle, and Fat in a Rat Model of Sleep Apnea: Differential Effect of Obstructive Apneas and Intermittent Hypoxia
    Almendros, Isaac
    Farre, Ramon
    Planas, Anna M.
    Torres, Marta
    Bonsignore, Maria R.
    Navajas, Daniel
    Montserrat, Josep M.
    SLEEP, 2011, 34 (08) : 1127 - 1133