Pancreatic mucinous cystadenoma with serum CA 19-9 over 1,000,000 U/mL: a case report and review of the literature

被引:2
作者
Costa, Wilson L., Jr. [1 ]
Mantoan, Henrique [1 ]
Brito, Rafael Horacio [1 ]
Ribeiro, Heber S. C. [1 ]
Diniz, Alessandro L. [1 ]
Godoy, Andre Luis [1 ]
Farias, Igor Correia [1 ]
Begnami, Maria Dirlei F. S. [2 ]
Soares, Fernando Augusto [2 ]
Coimbra, Felipe J. F. [1 ]
机构
[1] AC Camargo Canc Ctr, Dept Abdominal Surg, BR-01501900 Sao Paulo, Brazil
[2] AC Camargo Canc Ctr, Dept Surg Pathol, BR-01501900 Sao Paulo, Brazil
关键词
Pancreatic cystic lesions; Biomarkers; CA19-9; CARBOHYDRATE ANTIGEN 19-9; CYSTIC NEOPLASMS; CA19-9; LEVELS; ADENOCARCINOMA; DIAGNOSIS; EXPERIENCE; SURVIVAL; LESIONS; BENIGN;
D O I
10.1186/s12957-015-0476-y
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: The diagnosis of pancreatic cystic neoplasms has become more accurate recently. In some cases, however, doubt remains regarding the lesion's malignant potential. CA 19-9 has long been identified as a reliable biomarker in differentiating pancreatic benign and malignant lesions, especially in non-jaundiced patients. Case report and discussion: We report a case of a young female who presented with a mucinous lesion in the tail of the pancreas and a serum CA 19-9 over 1,000,000 U/mL. She was taken to surgery and had a distal pancreatectomy and splenectomy. Pathology reports showed only a mucinous cystadenoma. After 1 year of follow-up, her serum CA 19-9 was normal. Following that, the work-up in these lesions, the role of the biomarker in pancreatic adenocarcinoma and in the differentiation between benign and malignant lesions is discussed.
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