Combined Inhibition of Src and EGFR Abrogates Tumor-Stromal Interaction and Angiogenesis in Pancreatic Cancer In Vivo

被引：0
|
作者：
Nagaraj, N. S.
Revetta, F.
Washington, M. K.
Merchant, N. B.
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Surg, Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[2] Vanderbilt Univ, Med Ctr, Dept Pathol, Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA
来源：
PANCREAS | 2010年 / 39卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：1335 / 1336
页数：2
相关论文
共 50 条
  • [31] Targeting angiogenic pathways involving tumor-stromal interaction to treat advanced human prostate cancer
    Sokoloff, MH
    Chung, LWK
    CANCER AND METASTASIS REVIEWS, 1998, 17 (04) : 307 - 315
  • [32] Targeting Tumor Intrinsic p38 MAPK Signaling to Suppress Inflammatory Tumor-stromal Crosstalk in Pancreatic Cancer
    Singh, S.
    Dosch, A.
    Silva, I. De Castro
    Mehra, S.
    Bianchi, A.
    Garrido, V. Tonin
    Deshpande, N.
    Datta, J.
    Nagathihalli, N.
    Merchant, N.
    PANCREAS, 2021, 50 (07) : 1098 - 1098
  • [33] ITGA5 inhibition in pancreatic stellate cells re-educates the in vitro tumor-stromal crosstalk
    Tao Wang
    Jian Yang
    Juanli Mao
    Lizhi Zhu
    Xiu Luo
    Chao Cheng
    Lu Zhang
    Medical Oncology, 40
  • [34] The tumor-stromal interaction between the intraturnoral Wnt1 and the stromal VEGF-A is associated with angiogenesis in squamous cell carcinomas of the lung.
    Ishikawa, S
    Liu, D
    Nakano, J
    Nakashima, T
    Masuya, D
    Kontani, K
    Yokomise, H
    Huang, CL
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 668S - 668S
  • [35] Targeting Tumor-Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in Pancreatic Cancer
    Dosch, Austin R.
    Singh, Samara
    Dai, Xizi
    Mehra, Siddharth
    Silva, Iago De Castro
    Bianchi, Anna
    Srinivasan, Supriya
    Gao, Zhen
    Ban, Yuguang
    Chen, Xi
    Banerjee, Sulagna
    Nagathihalli, Nagaraj S.
    Datta, Jashodeep
    Merchant, Nipun B.
    MOLECULAR CANCER THERAPEUTICS, 2021, 20 (11) : 2280 - 2290
  • [36] Arl4c promotes the growth and drug resistance of pancreatic cancer by regulating tumor-stromal interactions
    Chen, Xin
    Zhang, Yanzhen
    Qian, Weikun
    Han, Liang
    Li, Wei
    Duan, Wanxing
    Wu, Zheng
    Wang, Zheng
    Ma, Qingyong
    ISCIENCE, 2021, 24 (12)
  • [37] Dual Src and EGFR inhibition in combination with gemcitabine in advanced pancreatic cancer: phase I results
    Cardin, Dana B.
    Goff, Laura W.
    Chan, Emily
    Whisenant, Jennifer G.
    Ayers, G. Dan
    Takebe, Naoko
    Arlinghaus, Lori R.
    Yankeelov, Thomas E.
    Berlin, Jordan
    Merchant, Nipun
    INVESTIGATIONAL NEW DRUGS, 2018, 36 (03) : 442 - 450
  • [38] Tumor-stromal interactions of the bone microenvironment: in vitro findings and potential in vivo relevance in metastatic lung cancer models
    Luis-Ravelo, Diego
    Anton, Iker
    Vicent, Silvestre
    Hernandez, Igor
    Valencia, Karmele
    Zandueta, Carolina
    Martinez-Canarias, Susana
    Gurpide, Alfonso
    Lecanda, Fernando
    CLINICAL & EXPERIMENTAL METASTASIS, 2011, 28 (08) : 779 - 791
  • [39] Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway
    Ide, Takao
    Kitajima, Yoshihiko
    Miyoshi, Atsushi
    Ohtsuka, Takao
    Mitsuno, Mayumi
    Ohtaka, Kazuma
    Koga, Yasuo
    Miyazaki, Kohji
    CANCER RESEARCH, 2006, 66 (08)
  • [40] Tumor-stromal cell interaction under hypoxia increases the invasiveness of pancreatic cancer cells through the hepatocyte growth factor/c-Met pathway
    Ide, Takao
    Kitajima, Yoshihiko
    Miyoshi, Atsushi
    Ohtsuka, Takao
    Mitsuno, Mayumi
    Ohtaka, Kazuma
    Koga, Yasuo
    Miyazaki, Kohji
    INTERNATIONAL JOURNAL OF CANCER, 2006, 119 (12) : 2750 - 2759
12345