Combined Inhibition of Src and EGFR Abrogates Tumor-Stromal Interaction and Angiogenesis in Pancreatic Cancer In Vivo

被引：0
|
作者：
Nagaraj, N. S.
Revetta, F.
Washington, M. K.
Merchant, N. B.
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Surg, Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[2] Vanderbilt Univ, Med Ctr, Dept Pathol, Vanderbilt Ingram Canc Ctr, Nashville, TN 37232 USA
来源：
PANCREAS | 2010年 / 39卷 / 08期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
引用
收藏
页码：1335 / 1336
页数：2
相关论文
共 50 条
  • [21] Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
    Ohuchida, K
    Mizumoto, K
    Murakami, M
    Qian, LW
    Sato, N
    Nagai, E
    Matsumoto, K
    Nakamura, T
    Tanaka, M
    CANCER RESEARCH, 2004, 64 (09) : 3215 - 3222
  • [22] Hypoxia Triggers Hedgehog-Mediated Tumor-Stromal Interactions in Pancreatic Cancer
    Spivak-Kroizman, Taly R.
    Hostetter, Galen
    Posner, Richard
    Aziz, Meraj
    Hu, Chengcheng
    Demeure, Michael J.
    Von Hoff, Daniel
    Hingorani, Sunil R.
    Palculict, Timothy B.
    Izzo, Julie
    Kiriakova, Galina M.
    Abdelmelek, Mena
    Bartholomeusz, Geoffrey
    James, Brian P.
    Powis, Garth
    CANCER RESEARCH, 2013, 73 (11) : 3235 - 3247
  • [23] Interaction of tumor and stromal cells in pancreatic cancer
    Gaedcke, Jochen
    Koenig, Alexander
    TRANSLATIONAL CANCER RESEARCH, 2017, 6 : S29 - S30
  • [24] Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions
    Zhengdong Jiang
    Cancan Zhou
    Liang Cheng
    Bin Yan
    Ke Chen
    Xin Chen
    Liang Zong
    Jianjun Lei
    Wanxing Duan
    Qinhong Xu
    Xuqi Li
    Zheng Wang
    Qingyong Ma
    Jiguang Ma
    Journal of Experimental & Clinical Cancer Research, 37
  • [25] Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions
    Jiang, Zhengdong
    Zhou, Cancan
    Cheng, Liang
    Yan, Bin
    Chen, Ke
    Chen, Xin
    Zong, Liang
    Lei, Jianjun
    Duan, Wanxing
    Xu, Qinhong
    Li, Xuqi
    Wang, Zheng
    Ma, Qingyong
    Ma, Jiguang
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2018, 37
  • [26] Blocking CXCLs-CXCR2 axis in tumor-stromal interaction contributes to the survival in a mouse model of pancreatic cancer
    Sano, Makoto
    Ijichi, Hideaki
    Tateishi, Keisuke
    Tada, Minoru
    Koike, Kazuhiko
    CANCER SCIENCE, 2018, 109 : 434 - 434
  • [27] Combined Src and EGFR inhibition targets STAT3 to induce stromal remodeling and increase drug delivery to improve survival in a mouse model of pancreatic cancer
    Dosch, Austin R.
    Dai, Xizi
    Reyzer, Michelle L.
    Kwon, Deukwoo
    Caprioli, Richard
    Merchant, Nipun B.
    Nagathihalli, Nagaraj S.
    CANCER RESEARCH, 2019, 79 (24)
  • [28] Cancer-Stromal Cell Interaction and Tumor Angiogenesis in Gastric Cancer
    Kitadai, Yasuhiko
    CANCER MICROENVIRONMENT, 2010, 3 (01) : 109 - 116
  • [29] Tumor-stromal interaction through the estrogen-signaling pathway in human breast cancer
    Yamaguchi, Y
    Takei, H
    Suemasu, K
    Kobayashi, Y
    Kurosumi, M
    Harada, N
    Hayashi, S
    CANCER RESEARCH, 2005, 65 (11) : 4653 - 4662
  • [30] ITGA5 inhibition in pancreatic stellate cells re-educates the in vitro tumor-stromal crosstalk
    Wang, Tao
    Yang, Jian
    Mao, Juanli
    Zhu, Lizhi
    Luo, Xiu
    Cheng, Chao
    Zhang, Lu
    MEDICAL ONCOLOGY, 2022, 40 (01)
12345