An indolizine-rhodamine based FRET fluorescence sensor for highly sensitive and selective detection of Hg2+ in living cells

被引：37
|
作者：
Ji, Ruixue [1 ]
Liu, Aikun [1 ]
Shen, Shili [1 ]
Cao, Xiaoqun [1 ]
Li, Fei [1 ]
Ge, Yanqing [1 ]
机构：
[1] Taishan Med Univ, Sch Chem & Pharmaceut Engn, Tai An 271000, Shandong, Peoples R China
来源：
RSC ADVANCES | 2017年 / 7卷 / 65期
关键词：
RESONANCE ENERGY-TRANSFER; PROBE; CHEMOSENSORS; SYSTEM; IONS; CHEMODOSIMETER; MECHANISMS; CU2+; DYAD;
D O I：
10.1039/c7ra07938a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An indolizine-rhodamine-based ratiometric fluorescent probe was designed and successfully synthesized. The probe shows a large Stokes shift (204 nm), high sensitivity and high selectivity. The detection limit was calculated to be as low as 8.76 nM. The probe could quickly (5 min) detect Hg2+ over a wide pH range from 5 to 10. Furthermore, it could be used for imaging Hg2+ in living cells.
引用
收藏
页码：40829 / 40833
页数：5
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