DIALYSIS Can plasma creatinine levels guide initiation of dialysis?

被引：5

作者：

Krediet, Raymond T. ^{[1
]}

Dekker, Friedo W. ^{[2
]}

机构：

[1] Acad Med Ctr, Div Nephrol, Dept Med, NL-1100 DE Amsterdam, Netherlands

[2] Leiden Univ, Med Ctr, Dept Clin Epidemiol, NL-2300 RC Leiden, Netherlands

来源：

NATURE REVIEWS NEPHROLOGY | 2010年 / 6卷 / 10期

关键词：

GLOMERULAR-FILTRATION-RATE; SERUM CREATININE; RENAL-FAILURE; SURVIVAL; COMORBIDITY; PREDICTION; START; STAGE;

D O I：

10.1038/nrneph.2010.109

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The results of a large observational study seem to confirm an association between early initiation of dialysis and increased mortality that is not fully explained by the presence of comorbidities and other confounding variables. However, this paradoxical association may be an artifact resulting from the inaccuracy of using plasma creatinine levels to estimate glomerular filtration rates in patients with severely impaired renal function.

引用

页码：563 / 564

页数：2

共 10 条

[1] Creatinine production, nutrition, and glomerular filtration rate estimation [J].

Beddhu, S ;

Samore, MH ;

Roberts, MS ;

Stoddard, GJ ;

Pappas, LM ;

Cheung, AK .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 (04) :1000-1005

[2] PREDICTION OF CREATININE CLEARANCE FROM SERUM CREATININE [J].

COCKCROFT, DW ;

GAULT, MH .

NEPHRON, 1976, 16 (01) :31-41

[3] Estimation of residual glomerular filtration rate in dialysis patients from the plasma cystatin C level [J].

Hoek, Frans J. ;

Korevaar, Johanna C. ;

Dekker, Friedo W. ;

Boeschoten, Elisabeth W. ;

Krediet, Raymond T. .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2007, 22 (06) :1633-1638

[4] At which stage of renal failure should dialysis be started? [J].

Jacobs, C .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2000, 15 (03) :305-307

[5] Effect of comorbidity on the increased mortality associated with early initiation of dialysis [J].

Kazmi, WH ;

Gilbertson, DT ;

Obrador, GT ;

Guo, HF ;

Pereira, BJG ;

Collins, AJ ;

Kausz, AT .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2005, 46 (05) :887-896

[6] When to initiate dialysis: effect of proposed US guidelines on survival [J].

Korevaar, JC ;

Jansen, MAM ;

Dekker, FW ;

Jager, KJ ;

Boeschoten, EW ;

Krediet, RT ;

Bossuyt, PMM .

LANCET, 2001, 358 (9287) :1046-1050

[7] Age and comorbidity may explain the paradoxical association of an early dialysis start with poor survival [J].

Lassalle, Mathilde ;

Labeeuw, Michel ;

Frimat, Luc ;

Villar, Emmanuel ;

Joyeux, Veronique ;

Couchoud, Cecile ;

Stengel, Benedicte .

KIDNEY INTERNATIONAL, 2010, 77 (08) :700-707

[8] A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation [J].

Levey, AS ;

Bosch, JP ;

Lewis, JB ;

Greene, T ;

Rogers, N ;

Roth, D .

ANNALS OF INTERNAL MEDICINE, 1999, 130 (06) :461-+

[9] Residual renal function at the start of dialysis and clinical outcomes [J].

Stel, Vianda S. ;

Dekker, Friedo W. ;

Ansell, David ;

Augustijn, Hans ;

Casino, Francesco G. ;

Collart, Frederic ;

Finne, Patrik ;

Ioannidis, George A. ;

Salomone, Mario ;

Traynor, Jamie P. ;

Zurriaga, Oscar ;

Verrina, Enrico ;

Jager, Kitty J. .

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2009, 24 (10) :3175-3182

[10] Early initiation of dialysis fails to prolong survival in patients with end-stage renal failure [J].

Traynor, JP ;

Simpson, K ;

Geddes, CC ;

Deighan, CJ ;

Fox, JG .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2002, 13 (08) :2125-2132

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