Colonization Versus Carriage of Clostridium difficile

被引：78

作者：

Donskey, Curtis J. ^{[1
]}

Kundrapu, Sirisha ^{[2
]}

Deshpande, Abhishek ^{[3
]}

机构：

[1] Louis Stokes Cleveland Vet Affairs Med Ctr, Infect Dis Sect, Cleveland, OH 44106 USA

[2] Case Western Reserve Univ, Sch Med, Dept Med, Div Infect Dis & HIV Med, Cleveland, OH 44106 USA

[3] Cleveland Clin, Inst Med, Dept Infect Dis, Cleveland, OH 44106 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 2015年 / 29卷 / 01期

关键词：

Clostridium difficile; Colonization; Antibiotic; Transmission; VOLATILE FATTY-ACIDS; NOSOCOMIAL ACQUISITION; ASYMPTOMATIC CARRIAGE; RISK-FACTORS; BILE-SALTS; INFECTION; TRANSMISSION; VANCOMYCIN; SPORES; PREVALENCE;

D O I：

10.1016/j.idc.2014.11.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Asymptomatic carriage of toxigenic strains of Clostridium difficile is common in health care facilities and the community. However, infection control efforts have traditionally focused almost entirely on symptomatic patients. There is now growing concern that asymptomatic carriers may be an underappreciated source of transmission. This article provides an overview of the pathogenesis and epidemiology of C difficile colonization, reviews the evidence that asymptomatic carriers shed spores and contribute to transmission, and examines practical issues related to prevention of transmission from carriers.

引用

页码：13 / +

页数：17

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