Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer

被引:13
作者
Ahn, A
Yang, CH
Wax, A
Popescu, G
Fang-Yen, C
Badizadegan, K
Dasari, RR
Feld, MS
机构
[1] MIT, GR Harrison Spect Lab, Cambridge, MA 02139 USA
[2] Massachusetts Gen Hosp, Boston, MA 02114 USA
关键词
Dispersion (waves) - Imaging techniques - Microscopic examination - Optical beam splitters - Perturbation techniques - Scanning - Tomography;
D O I
10.1364/AO.44.001188
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Harmonic phase-dispersion microscopy (PDM) is a new imaging technique in which contrast is provided by differences in refractive index at two harmonically related wavelengths. We report a new configuration of the harmonic phase-dispersion microscope in a Mach-Zehnder geometry as an instrument for imaging biological samples. Several improvements on the earlier design are demonstrated, including a single-pass configuration and acousto-optic modulators for generating the heterodyne signals without mechanical arm scanning. We demonstrate quantitative phase-dispersion images of test structures and biological samples. (C) 2005 Optical Society of America.
引用
收藏
页码:1188 / 1190
页数:3
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