Three-dimensional structure-activity relationship modeling of digoxin inhibition and docking to Na+,K+-ATPase

被引：3
|
作者：
Ball, WJ [1 ]
Farr, CD
Paula, S
Keenan, SM
Delisle, RK
Welsh, WJ
机构：
[1] Univ Cincinnati, Coll Med, Cincinnati, OH 45267 USA
[2] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Piscataway, NJ 08845 USA
[3] Accelrys, Princeton, NJ 08543 USA
来源：
NA,K-ATPASE AND RELATED CATION PUMPS: STRUCTURE, FUNCTION, AND REGULATORY MECHANISMS | 2003年 / 986卷
关键词：
digoxin docking; structural modeling; 3D-QSAR; Na+-pump structure;
D O I：
10.1111/j.1749-6632.2003.tb07191.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：296 / 297
页数：2
相关论文
共 50 条
  • [1] Three-dimensional quantitative structure-activity relationship modeling of digoxin inhibition of Na+,K+-ATPase
    Ball, WJ
    Farr, C
    Tabet, M
    Burd, C
    Wang, X
    Welsh, W
    BIOPHYSICAL JOURNAL, 2002, 82 (01) : 260A - 260A
  • [2] Quantitative Structure-Activity Relationship Studies on Na+,K+-ATPase Inhibitors
    Gupta, Satya P.
    CHEMICAL REVIEWS, 2012, 112 (06) : 3171 - 3192
  • [3] Modeling of the three-dimensional structure of the digitalis intercalating matrix in Na+/K+-ATPase protodimer
    Repke, KRH
    Weiland, J
    Megges, R
    Schon, R
    JOURNAL OF ENZYME INHIBITION, 1996, 10 (03): : 147 - 157
  • [4] A quantitative structure-activity relationship study on a series of Na+, K+-ATPase inhibitors
    Gupta, SP
    Bagaria, P
    Kumaran, S
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2004, 19 (05) : 389 - 393
  • [5] Na+/K+-ATPase: Activity and inhibition
    Colovic, M.
    Krstic, D.
    Krinulovic, K.
    Momic, T.
    Savic, J.
    Vujacic, A.
    Vasic, V.
    RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY A, 2009, 83 (09) : 1602 - 1608
  • [6] Na+/K+-ATPase: Activity and inhibition
    M. Čolović
    D. Krstić
    K. Krinulović
    T. Momić
    J. Savić
    A. Vujačić
    V. Vasić
    Russian Journal of Physical Chemistry A, 2009, 83 : 1602 - 1608
  • [7] Inhibition of Na+,K+-ATPase by flavonoids and their positive inotropic effect.: Investigation of the structure-activity relationship
    Umarova, FT
    Khushbactova, ZA
    Batirov, EH
    Mekler, VM
    BIOLOGICHESKIE MEMBRANY, 1998, 15 (01): : 24 - 35
  • [8] Three-dimensional quantitative structure -: Activity relationship study of the inhibition of Na+,K+-ATPase by cardiotonic steroids using comparative molecular field analysis
    Farr, CD
    Burd, C
    Tabet, MR
    Wang, X
    Welsh, WJ
    Ball, WJ
    BIOCHEMISTRY, 2002, 41 (04) : 1137 - 1148
  • [9] Na+,K+-ATPase as a docking station: protein–protein complexes of the Na+,K+-ATPase
    Linda Reinhard
    Henning Tidow
    Michael J. Clausen
    Poul Nissen
    Cellular and Molecular Life Sciences, 2013, 70 : 205 - 222
  • [10] TISSUE UPTAKE OF DIGOXIN AND NA+,K+-ATPASE ACTIVITY IN HYPERTHYROIDISM
    ANSARI, AF
    LAWRENCE, JR
    THOMPSON, GG
    SUMMER, DJ
    KEXUE TONGBAO, 1982, 27 (08): : 893 - 897
12345