Design, synthesis and biological evaluation of macrocyclic derivatives as TRK inhibitors (vol 53,128409,2021)

被引:0
作者
Li, Pei [1 ]
Cai, Shi [2 ]
Zhao, Tong [1 ]
Xu, Lin [1 ]
Guan, Dezhong [2 ]
Li, Jinruo [3 ]
Zhou, Jinpei [1 ]
Zhang, Huibin [2 ]
机构
[1] China Pharmaceut Univ, Dept Med Chem, 24 Tongjiaxiang, Nanjing 210009, Peoples R China
[2] China Pharmaceut Univ, Ctr Drug Discovery, State Key Lab Nat Med, 24 Tongjiaxiang, Nanjing 210009, Peoples R China
[3] China Pharmaceut Univ, Coll Pharm, 24 Tongjiaxiang, Nanjing 210009, Peoples R China
关键词
D O I
10.1016/j.bmcl.2021.128502
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Design, synthesis and biological evaluation of tyrosine derivatives as Mcl-1 inhibitors
    Liu, Lulu
    Liu, Renshuai
    Yang, Xinying
    Hou, Xuben
    Fang, Hao
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 191
  • [32] Design, synthesis, and biological evaluation of symmetrical azine derivatives as novel tyrosinase inhibitors
    Somaye Karimian
    Fatemeh Kazemi
    Mahshid Attarroshan
    Maryam Gholampour
    Shiva Hemmati
    Amirhossein Sakhteman
    Yasaman Behzadipour
    Maryam Kabiri
    Aida Iraji
    Mehdi Khoshneviszadeh
    BMC Chemistry, 15
  • [33] Design, synthesis, and biological evaluation of symmetrical azine derivatives as novel tyrosinase inhibitors
    Karimian, Somaye
    Kazemi, Fatemeh
    Attarroshan, Mahshid
    Gholampour, Maryam
    Hemmati, Shiva
    Sakhteman, Amirhossein
    Behzadipour, Yasaman
    Kabiri, Maryam
    Iraji, Aida
    Khoshneviszadeh, Mehdi
    BMC CHEMISTRY, 2021, 15 (01)
  • [34] Design, synthesis and biological evaluation of novel diarylpyridine derivatives as tubulin polymerisation inhibitors
    Yang, Shanbo
    Wang, Chao
    Shi, Lingyu
    Chang, Jing
    Zhang, Yujing
    Meng, Jingsen
    Liu, Wenjing
    Zeng, Jun
    Zhang, Renshuai
    Shao, Yingchun
    Xing, Dongming
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 37 (01) : 2755 - 2764
  • [35] Design, synthesis and biological evaluation of dihydroquinoxalinone derivatives as BRD4 inhibitors
    Yang, Yifei
    Zhao, Leilei
    Xu, Bin
    Yang, LingYun
    Zhang, Jian
    Zhang, Huibin
    Zhou, Jinpei
    BIOORGANIC CHEMISTRY, 2016, 68 : 236 - 244
  • [36] Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors
    Paramashivappa, R
    Kumar, PP
    Rao, PVS
    Rao, AS
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (04) : 657 - 660
  • [37] Design, synthesis and biological evaluation of spiropyrazolopyridone derivatives as potent dengue virus inhibitors
    Xu, Jimin
    Xie, Xuping
    Chen, Haiying
    Zou, Jing
    Xue, Yu
    Ye, Na
    Shi, Pei-Yong
    Zhou, Jia
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 30 (11)
  • [38] Design, synthesis and biological evaluation of 2-phenylaminopyrimidine derivatives as EGFR inhibitors
    Tang, Chunlei
    Wang, Jie
    Wang, Dong
    Wang, Huabing
    Cui, Shengkai
    Xiao, Tianxin
    Fan, Weizheng
    Zhang, Yan
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 101
  • [39] Design, synthesis and biological evaluation of novel zanamivir derivatives as potent neuraminidase inhibitors
    Cheng, Li Ping
    Wang, Tian Chi
    Yu, Rao
    Li, Meng
    Huang, Jin Wen
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (23-24) : 3622 - 3629
  • [40] Design, synthesis, and biological evaluation of acetophenone derivatives as dual binding acetylcholinesterase inhibitors
    Shen, Yanhong
    Li, Baoli
    Xu, Hu
    Zhang, Guoqiang
    PHARMAZIE, 2013, 68 (05): : 307 - 310