Ethyl 5-ethoxy-3-methyl-1H-indole-2-carboxylate

被引:8
|
作者
Chandrakantha, TN
Puttaraja
Kokila, MK
Shivaprakash, NC
机构
[1] Bangalore Univ, Dept Phys, Bangalore 560056, Karnataka, India
[2] Indian Inst Sci, Dept Instrumentat, Bangalore 560012, Karnataka, India
关键词
D O I
10.1107/S010827019800568X
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The title compound, C14H17NO3, having an ethoxycarbonyl group at C2, serves as an important precursor in the synthesis of fused-indole heterocycles of biological importance. The indole moiety is planar and it forms dihedral angles of 2.3(1) and 3.9(1)degrees with the ethoxycarbonyl group at C2 and the ethoxy group at C5, respectively. The centrosymmetrically related molecules are held together by hydrogen bonds across a centre of symmetry and form dimers.
引用
收藏
页码:1685 / 1687
页数:3
相关论文
共 50 条
  • [41] 3-(5-Ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole
    Seferoglu, Zeynel
    Hokelek, Tuncer
    Sahin, Ertan
    Ertan, Nermin
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O568 - O570
  • [42] Crystal structure of methyl 5-methoxy 1H-indole-2-carboxylate, C11H11NO3
    Attia, Mohamed I.
    Ghabbour, Hazem A.
    Fun, Hoong-Kun
    ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES, 2016, 231 (01): : 313 - 314
  • [43] Ethyl 5-hydroxy-3-(3-methoxybenzoyl)-1′,5-di-methyl-2′-oxo-4,5-dihydro-1′H-spiro[furan-2(3H), 3′(2′H)-indole]-4-carboxylate
    Gayathri, D.
    Velmurugan, D.
    Ravikumar, K.
    Savitha, G.
    Perumal, P. T.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O5947 - O5949
  • [44] Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate
    J. Balzarini
    E. A. Ruchko
    E. K. Zakharova
    I. Yu. Kameneva
    M. B. Nawrozkij
    Chemistry of Heterocyclic Compounds, 2014, 50 : 489 - 495
  • [45] Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate
    Balzarini, J.
    Ruchko, E. A.
    Zakharova, E. K.
    Kameneva, I. Yu.
    Nawrozkij, M. B.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2014, 50 (04) : 489 - 495
  • [46] Ethyl 5-amino-1-(5-amino-3-methyl-1-phenyl-1H-pyrazol-4-ylcarbonyl)3-methyl-1H-pyrazole-4-carboxylate
    Li, JF
    Song, HB
    Zhu, YQ
    Yang, HZ
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O1756 - O1758
  • [47] Methyl 4-benzyloxy-7-methoxy-1methyl-1H-indole- 2-carboxylate
    Wang, Peng
    Xing, Hualu
    Liu, Yang
    Xie, Wencheng
    Zhao, Guisen
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : 02480 - +
  • [48] 5-Methyl-1H-indole-3-carbaldehyde
    Ismail, Sharifah Shafiqah
    Khaledi, Hamid
    Ali, Hapipah Mohd
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O2691 - +
  • [49] Ethyl 3-methyl-1-oxo-4H-1,4-benzothiazine-2-carboxylate
    Akkurt, M
    Türktekin, S
    Baryala, Y
    Zerzouf, A
    Salem, M
    Essassi, E
    Büyükgüngör, O
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O2716 - O2717
  • [50] Ethyl 5-cyano-1H-pyrrole-2-carboxylate
    Zhang, YH
    Yin, ZM
    Li, XF
    He, JQ
    Cheng, JP
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2003, 59 : O1881 - O1882