X-ray monitoring of laser interstitial thermotherapy (LITT) in ex vivo porcine tissue

被引：1

作者：

Minhaj, AM ^{[1
]}

Manns, F ^{[1
]}

Milne, PJ ^{[1
]}

Denham, DB ^{[1
]}

Salas, N ^{[1
]}

Parel, JM ^{[1
]}

Robinson, DS ^{[1
]}

机构：

[1] Univ Miami, Bascom Palmer Eye Inst, Ophthalm Biophys Ctr, Miami, FL 33152 USA

来源：

LASERS IN SURGERY: ADVANCED CHARACTERIZATION THERAPEUTICS, AND SYSTEMS XI | 2001年 / 4244卷

关键词：

LITT; laser hyperthermia; breast cancer; monitoring; temperature; mammography;

D O I：

10.1117/12.427841

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Experiments on the feasibility of X-ray monitoring of laser interstitial thermotherapy (LITT) of breast cancer are presented. Digital images of heated tissue phantoms (including fatty porcine tissue and polyacrylamide/acrylate hydrogel), obtained from an X-ray stereotactic biopsy system, were analyzed for changes in pixel intensity. Tissue phantoms were heated either by a 980 nm diode laser or by resistive heating elements in a custom-made chamber. Analysis was conducted by evaluating the changes in average pixel intensity of regions of interest. Image constancy and stability of the X-ray system were also investigated. Slight changes (<5%) dependent on the temperature of the tissue phantom were observed, while changes caused by heat-induced tissue displacement and/or shrinkage were more significant (> 10%).

引用

页码：500 / 507

页数：8

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