Secondary Malignant Neoplasms After Childhood Cancer

被引：12

作者：

Varan, Ali ^{[1
]}

Kebudi, Rejin ^{[2
]}

机构：

[1] Hacettepe Univ, Inst Oncol, Dept Pediat Oncol, TR-06100 Ankara, Turkey

[2] Istanbul Univ, Cerahpasa Med Fac, Dept Pediat Oncol, Istanbul, Turkey

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2011年 / 28卷 / 05期

关键词：

cancer; children; chemotherapy; etiology; radiotherapy; secondary malignant neoplasms; ACUTE LYMPHOBLASTIC-LEUKEMIA; BREAST-CANCER; 2ND NEOPLASMS; PEDIATRIC-PATIENTS; THYROID-CARCINOMA; HODGKINS-DISEASE; BRAIN-TUMORS; SOFT-TISSUE; RADIATION; RISK;

D O I：

10.3109/08880018.2011.553879

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Overall survival from cancer has greatly improved, although it still remains the second leading cause of mortality in the world. This result was achieved through the use of chemotherapy and radiotherapy, which are severely toxic to normal tissues. In the long-term follow-up of cancer patients, the development of secondary malignant disease is common and it is one of the most severe side effects of cancer treatment. Physicians aim to decrease this toxicity and reduce the development of secondary cancers. In this study, the epidemiology and etiology of second malignant neoplasms are reviewed.

引用

页码：345 / 353

页数：9

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