Contemporary Imaging of the Surgically Placed Hepatic Arterial Infusion Chemotherapy Pump

被引:5
作者
Strnad, Benjamin S. [1 ]
Ludwig, Daniel R. [1 ]
Gilcrease-Garcia, Brian [2 ]
Fraum, Tyler J. [1 ]
Shetty, Anup S. [1 ]
Doyle, Maria B. Majella [3 ]
Mellnick, Vincent M. [1 ]
机构
[1] Washington Univ, Mallinckrodt Inst Radiol, Sch Med, 510 S Kingshighway Blvd,Campus Box 8131, St Louis, MO 63110 USA
[2] Northwestern Univ, Feinberg Sch Med, Dept Radiol, Chicago, IL 60611 USA
[3] Washington Univ, Sch Med, Dept Surg, St Louis, MO 63110 USA
关键词
complications; HAI; hepatic arterial infusion chemotherapy; hepatic artery; COLORECTAL LIVER METASTASES; REGIONAL CHEMOTHERAPY; SYSTEMIC CHEMOTHERAPY; CANCER; RESECTION; COMPLICATIONS; SURVIVAL; ANATOMY; SURGERY; FUDR;
D O I
10.2214/AJR.20.24437
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Hepatic arterial infusion (HAI) of chemotherapy is a locoregional treatment strategy for hepatic malignancy involving placement of a surgically implanted pump or percutaneous port-catheter device into a branch of the hepatic artery. HAI has been used for metastatic colorectal cancer for decades but has recently attracted new attention because of its potential impact on survival, when combined with systemic therapy, in patients presenting with unresectable hepatic disease. Although various HAI device-related complications have been described, little attention has been given to their appearance on imaging. Radiologists are uniquely positioned to identify these complications given that patients receiving HAI therapy typically undergo frequent imaging and may have complications that are delayed or clinically unsuspected. Therefore, this article reviews the multimodality imaging considerations of surgically implanted HAI devices. The role of imaging in routine perioperative assessment, including the normal postoperative appearance of the device, is described. The imaging findings of potential complications, including pump pocket complications, catheter or arterial complications, and toxic or ischemic complications, are presented, with a focus on CT. Familiarity with the device and its complications will aid radiologists in playing an important role in the treatment of patients undergoing HAI therapy.
引用
收藏
页码:633 / 643
页数:11
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