Rhodium-Catalyzed Selective Olefination of Arene Esters via C-H Bond Activation

被引：264

作者：

Park, Sae Hume

Kim, Ji Young

Chang, Sukbok ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea

来源：

ORGANIC LETTERS | 2011年 / 13卷 / 09期

关键词：

BENZOIC-ACIDS; AROMATIC KETONES; INTERNAL ALKYNES; CARBOXYLIC-ACIDS; DIRECT AMINATION; DIRECT ARYLATION; ARYL KETONES; DERIVATIVES; ALKENES; FUNCTIONALIZATION;

D O I：

10.1021/ol200600p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new catalytic procedure of ortho-olefination of benzoates and benzaldehydes has been developed. Ester and carboxaldehyde units were revealed to be effective chelating groups in focusing the activation of aryl C-H bonds ortho to the directing moieties under the Rh-catalyzed oxidative conditions. The reaction is highly regioselective with a range of benzoates and benzaldehydes enabling the efficient olefination with acrylates, acrylic acid, and styrenes.

引用

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页码：2372 / 2375

页数：4

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